Role of arginine salts in preventing freezing-induced increase in subvisible particles in protein formulations.

Munjal, Bhushan; Patel, Sajal M; Suryanarayanan, Raj

Munjal, Bhushan; Patel, Sajal M; Suryanarayanan, Raj.

Afiliación

Munjal B; Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, United States.
Patel SM; Dosage Form Design & Development, Biopharmaceutical Development, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD 20878, United States.
Suryanarayanan R; Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, United States. Electronic address: surya001@umn.edu.

Int J Pharm ; 619: 121694, 2022 May 10.

Article en En | MEDLINE | ID: mdl-35331829

Asunto(s)

Arginina; Sales (Química); Rastreo Diferencial de Calorimetría; Liofilización; Congelación; Manitol/química; Proteínas

Palabras clave

Arginine hydrochloride; Arginine salts; Counterions; Crystallization; Mannitol; Protein aggregation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arginina / Sales (Química) Idioma: En Revista: Int J Pharm Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos

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