Fluorescence-Based Binding Characterization of Small Molecule Ligands Targeting CUG RNA Repeats.

Chang, Zhihua; Zheng, Ya Ying; Mathivanan, Johnsi; Valsangkar, Vibhav A; Du, Jinxi; Abou-Elkhair, Reham A I; Hassan, Abdalla E A; Sheng, Jia

Chang, Zhihua; Zheng, Ya Ying; Mathivanan, Johnsi; Valsangkar, Vibhav A; Du, Jinxi; Abou-Elkhair, Reham A I; Hassan, Abdalla E A; Sheng, Jia.

Afiliación

Chang Z; Department of Chemistry and The RNA Institute, University at Albany, State University of New York, 1400 Washington Avenue, Albany, NY 12222, USA.
Zheng YY; Department of Chemistry and The RNA Institute, University at Albany, State University of New York, 1400 Washington Avenue, Albany, NY 12222, USA.
Mathivanan J; Department of Chemistry and The RNA Institute, University at Albany, State University of New York, 1400 Washington Avenue, Albany, NY 12222, USA.
Valsangkar VA; Department of Chemistry and The RNA Institute, University at Albany, State University of New York, 1400 Washington Avenue, Albany, NY 12222, USA.
Du J; Department of Chemistry and The RNA Institute, University at Albany, State University of New York, 1400 Washington Avenue, Albany, NY 12222, USA.
Abou-Elkhair RAI; Applied Nucleic Acids Research Center & Chemistry Department, Faculty of Science, Zagazig University, Zagazig 44523, Egypt.
Hassan AEA; Applied Nucleic Acids Research Center & Chemistry Department, Faculty of Science, Zagazig University, Zagazig 44523, Egypt.
Sheng J; Department of Chemistry and The RNA Institute, University at Albany, State University of New York, 1400 Washington Avenue, Albany, NY 12222, USA.

Int J Mol Sci ; 23(6)2022 Mar 19.

Article en En | MEDLINE | ID: mdl-35328743

Asunto(s)

Distrofia Miotónica; ARN; Fluorescencia; Humanos; Ligandos; Distrofia Miotónica/genética; ARN/genética; Proteínas de Unión al ARN/metabolismo; Sisomicina

Palabras clave

CUG repeat; RNA-ligand binding; aminoglycosides; fluorescence spectroscopy; microsatellite RNA expansions

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN / Distrofia Miotónica Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

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