Exosomal Carboxypeptidase E (CPE) and CPE-shRNA-Loaded Exosomes Regulate Metastatic Phenotype of Tumor Cells.

Hareendran, Sangeetha; Albraidy, Bassam; Yang, Xuyu; Liu, Aiyi; Breggia, Anne; Chen, Clark C; Loh, Y Peng

Hareendran, Sangeetha; Albraidy, Bassam; Yang, Xuyu; Liu, Aiyi; Breggia, Anne; Chen, Clark C; Loh, Y Peng.

Afiliación

Hareendran S; Section on Cellular Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Albraidy B; Section on Cellular Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Yang X; Section on Cellular Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Liu A; Biostatistics & Bioinformatics Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Breggia A; Maine Medical Center BioBank, Portland, ME 04074, USA.
Chen CC; Department of Neurosurgery, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Loh YP; Section on Cellular Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

Int J Mol Sci ; 23(6)2022 Mar 14.

Article en En | MEDLINE | ID: mdl-35328535

Asunto(s)

Carcinoma Hepatocelular; Exosomas; Neoplasias Hepáticas; MicroARNs; Carboxipeptidasa H/genética; Carcinogénesis/genética; Carcinoma Hepatocelular/metabolismo; Línea Celular Tumoral; Proliferación Celular/genética; Ciclina D1/metabolismo; Exosomas/metabolismo; Regulación Neoplásica de la Expresión Génica; Células HEK293; Humanos; Neoplasias Hepáticas/metabolismo; MicroARNs/genética; Fenotipo; Proyectos Piloto; ARN Mensajero/metabolismo; ARN Interferente Pequeño/genética; ARN Interferente Pequeño/metabolismo

Palabras clave

cancer proliferation; cancer therapy; diagnostic biomarker; engineered exosomes; hepatocellular carcinoma; metastasis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / MicroARNs / Exosomas / Neoplasias Hepáticas Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

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