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Androgen receptor activity in T cells limits checkpoint blockade efficacy.
Guan, Xiangnan; Polesso, Fanny; Wang, Chaojie; Sehrawat, Archana; Hawkins, Reed M; Murray, Susan E; Thomas, George V; Caruso, Breanna; Thompson, Reid F; Wood, Mary A; Hipfinger, Christina; Hammond, Scott A; Graff, Julie N; Xia, Zheng; Moran, Amy E.
Afiliación
  • Guan X; Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA.
  • Polesso F; Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR, USA.
  • Wang C; Genentech, Inc., South San Francisco, CA, USA.
  • Sehrawat A; Cell, Developmental and Cancer Biology, Oregon Health and Science University, Portland, OR, USA.
  • Hawkins RM; Cell, Developmental and Cancer Biology, Oregon Health and Science University, Portland, OR, USA.
  • Murray SE; Bristol Myers Squibb, New Brunswick, NJ, USA.
  • Thomas GV; Cell, Developmental and Cancer Biology, Oregon Health and Science University, Portland, OR, USA.
  • Caruso B; Cell, Developmental and Cancer Biology, Oregon Health and Science University, Portland, OR, USA.
  • Thompson RF; Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR, USA.
  • Wood MA; Department of Biology, University of Portland, Portland, OR, USA.
  • Hipfinger C; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.
  • Hammond SA; Department of Pathology and Laboratory Medicine, Oregon Health and Science University, Portland, OR, USA.
  • Graff JN; Cell, Developmental and Cancer Biology, Oregon Health and Science University, Portland, OR, USA.
  • Xia Z; Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA.
  • Moran AE; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.
Nature ; 606(7915): 791-796, 2022 06.
Article en En | MEDLINE | ID: mdl-35322234
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Receptores Androgénicos / Linfocitos T CD8-positivos / Inmunoterapia Límite: Humans / Male Idioma: En Revista: Nature Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Receptores Androgénicos / Linfocitos T CD8-positivos / Inmunoterapia Límite: Humans / Male Idioma: En Revista: Nature Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido