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[Practical guide to the use of thiopurinesin patients with inflammatory bowel diseases].
Zhao, Mirabella; Wewer, Mads Damsgaard; Bjerrum, Jacob Tveiten; Steenholdt, Casper; Schiødt, Frank; Haderslev, Kent; Kiszka-Kanowitz, Marianne; Munkholm, Pia; Seidelin, Jakob; Burisch, Johan.
Afiliación
  • Zhao M; Gastroenheden, Københavns Universitetshospital - Hvidovre Hospital.
  • Wewer MD; Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Københavns Universitetshospital - Hvidovre Hospital.
  • Bjerrum JT; Gastroenheden, Københavns Universitetshospital - Hvidovre Hospital.
  • Steenholdt C; Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Københavns Universitetshospital - Hvidovre Hospital.
  • Schiødt F; Det Sundhedsvidenskabelige Fakultet, Københavns Universitet.
  • Haderslev K; Medicinsk Klinik, Afdeling for Mave-, Tarm- og Leverlidelser, Københavns Universitetshospital - Herlev Hospital.
  • Kiszka-Kanowitz M; Medicinsk Klinik, Afdeling for Mave-, Tarm- og Leverlidelser, Københavns Universitetshospital - Herlev Hospital.
  • Munkholm P; Abdominalcenter K, Københavns Universitetshospital - Bispebjerg Hospital.
  • Seidelin J; Infektionsepidemiologi og Forebyggelse, Statens Serum Institut.
  • Burisch J; Afdeling for Infektionssygdomme, Københavns Universitetshospital - Rigshospitalet.
Ugeskr Laeger ; 184(11)2022 03 14.
Article en Da | MEDLINE | ID: mdl-35315759
Despite the increasing availability of biological treatment in recent years, thiopurines remain an important treatment option in patients with inflammatory bowel diseases (IBD) both as monotherapy and in combination therapy with biologicals. Pre-treatment screening of thiopurine-methyltransferase activity and monitoring of thiopurine metabolites during treatment are essential to optimize the effectiveness and safety of thiopurines. This review provides an evidence-based practical guide to prescribing and monitoring thiopurines in patients with IBD.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Inflamatorias del Intestino / Mercaptopurina Límite: Humans Idioma: Da Revista: Ugeskr Laeger Año: 2022 Tipo del documento: Article Pais de publicación: Dinamarca
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Inflamatorias del Intestino / Mercaptopurina Límite: Humans Idioma: Da Revista: Ugeskr Laeger Año: 2022 Tipo del documento: Article Pais de publicación: Dinamarca