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Serrated polyposis syndrome with multiple inverted lesions in the colon: Case report and elucidation of morphogenetic mechanism.
Yoshikawa, Chihiro; Koyama, Fumikazu; Morita, Kohei; Kuge, Hiroyuki; Nakamoto, Takayuki; Obara, Shinsaku; Iwasa, Yosuke; Kunishige, Tomohiro; Ohbayashi, Chiho; Sho, Masayuki.
Afiliación
  • Yoshikawa C; Department of Surgery Nara Medical University Nara Japan.
  • Koyama F; Department of Surgery Nara Medical University Nara Japan.
  • Morita K; Division of Endoscopy Nara Medical University Hospital Nara Japan.
  • Kuge H; Department of Diagnostic Pathology Nara Medical University Nara Japan.
  • Nakamoto T; Department of Surgery Nara Medical University Nara Japan.
  • Obara S; Department of Surgery Nara Medical University Nara Japan.
  • Iwasa Y; Division of Endoscopy Nara Medical University Hospital Nara Japan.
  • Kunishige T; Department of Surgery Nara Medical University Nara Japan.
  • Ohbayashi C; Department of Surgery Nara Medical University Nara Japan.
  • Sho M; Department of Surgery Nara Medical University Nara Japan.
DEN Open ; 2(1): e13, 2022 Apr.
Article en En | MEDLINE | ID: mdl-35310715
A 70-year-old man underwent surveillance colonoscopy following surgery for occlusive sigmoid colon cancer. The procedure revealed nine sessile serrated lesions (SSLs), including three inverted lesions. Endoscopic and surgical resections were performed. All nine lesions were confirmed pathologically as SSL, and the patient was diagnosed with serrated polyposis syndrome (SPS). Three inverted SSLs (iSSLs) showed endophytic growth without epithelial misplacement. Crypt analysis revealed that iSSL crypts were wider at the bottom than the opening, roughly resembling a frustoconical shape. Our results suggest that a horizontal arrangement of frustoconical crypts leads to hemispherical deformation of the muscularis mucosa, forming an inverted shape. This is the first report to reveal the morphogenesis of iSSLs from the shape of the crypt.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: DEN Open Año: 2022 Tipo del documento: Article Pais de publicación: Australia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: DEN Open Año: 2022 Tipo del documento: Article Pais de publicación: Australia