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Association of Impaired Fasting Blood Glucose With Triple Coronary Artery Stenosis and Myocardial Infarction Among Patients With Coronary Artery Stenosis.
Chen, Chang; Chen, Yequn; Xiao, Jiaxin; Zhang, Yanhong; Yang, Zhaorui; Yang, Peixuan; Lu, Nan; Yi, Kaihong; Chen, Xiaojun; Chen, Shaoxin; O'Gara MSc, Mary Clare; O'Meara, Michael; Ye, Shu; Tan, Xuerui.
Afiliación
  • Chen C; The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
  • Chen Y; The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
  • Xiao J; The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
  • Zhang Y; The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
  • Yang Z; The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
  • Yang P; The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
  • Lu N; The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
  • Yi K; The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
  • Chen X; The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
  • Chen S; The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
  • O'Gara MSc MC; The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
  • O'Meara M; The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
  • Ye S; The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
  • Tan X; Shantou University Medical College, Shantou, China.
Front Cell Dev Biol ; 10: 820124, 2022.
Article en En | MEDLINE | ID: mdl-35309914
Background: The association between impaired fasting glucose level (IFG) and coronary heart disease (CAD) remain controversial. In the present study, we sought to ascertain a relationship of IFG with the number of diseased coronary artery and occurrence of myocardial infarction, among CAD cases. Methods: We studied 1,451 consecutive no-diabetic patients who underwent coronary angiography at the First Affiliated Hospital of Shantou University Medical College in Southern China. Demographic, biochemical, clinical and angiographic data were collected. Results: The prevalence of IFG was higher in patients with angiographically confirmed CAD than in subjects without angiographic evidence of CAD (33.4 versus 28.2%, p = 0.034). Compared with CAD cases without IFG, CAD cases with IFG had a higher odds ratio (OR) of having triple-vessel disease as opposed to having single- or double-vessel disease [OR = 1.53, 95% confidence interval (CI) = 1.13-2.07]. Furthermore, the occurrence of MI was higher in CAD cases with IFG than in CAD cases without IFG (OR = 1.73, 95% CI = 1.27-2.36). Conclusions: There is an association between IFG and a predisposition to severe CAD indicated by triple vessel disease or myocardial infarction.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: Front Cell Dev Biol Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: Front Cell Dev Biol Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza