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Acellular nerve grafts with bone marrow mesenchymal stem cells/Schwann cells for sciatic nerve regeneration in rats: a meta-analysis.
Liang, Jie; Luo, Liang; Xiang, Feifan; Lan, Shuang-Li; Tan, Xiao-Qi; Gu, Hao; Yang, Kai-Wen; Ye, Junwu; Tang, Lian; Yang, Yunkang.
Afiliación
  • Liang J; Department of Bone and Joint Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Luo L; Department of Bone and Joint Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Xiang F; Department of Bone and Joint Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Lan SL; Department of Hepatobiliary Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Tan XQ; Department of Dermatology, Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Gu H; Department of Bone and Joint Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Yang KW; Department of Bone and Joint Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Ye J; Department of Bone and Joint Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Tang L; Department of Bone and Joint Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Yang Y; Department of Bone and Joint Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, China - yunk4ng@yandex.com.
J Neurosurg Sci ; 67(2): 241-247, 2023 Apr.
Article en En | MEDLINE | ID: mdl-35301841
INTRODUCTION: The aim of this meta-analysis was to evaluate the effects of acellular nerve grafts (ANGs) with bone marrow mesenchymal stem cells (BMSCs) or Schwann cells (SCs) on the treatment of sciatic nerve defect in rats. EVIDENCE ACQUISITION: Electronic databases were accessed to identify eligible targets. ANGs data were extracted for meta-analysis using Review Manager 5.3. EVIDENCE SYNTHESIS: The rats subjected to ANGs+BMSCs or ANGs+SCs are characterized by different sciatic nerve function index, nerve conduction, latency, amplitude, myelin sheath thickness, myelinated nerve fibers and gastrocnemius wet weight. accompanied with evidently superior recovery of limb function. These differences are of statistical significance (P<0.05) when compared to that of control group with ANGs only. CONCLUSIONS: ANGs with BMSCs or SCs can promote nerve regeneration and functional recovery in peripheral nerve defects.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células de Schwann / Células Madre Mesenquimatosas Tipo de estudio: Systematic_reviews Límite: Animals Idioma: En Revista: J Neurosurg Sci Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Italia
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células de Schwann / Células Madre Mesenquimatosas Tipo de estudio: Systematic_reviews Límite: Animals Idioma: En Revista: J Neurosurg Sci Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Italia