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The Role of redo-Sentinel Lymph Node Biopsy in Patients With Prior Ipsilateral Breast Cancer Surgery.
Macnab, Margo-Rose F; Slater, Gabrielle; Fuller, Mairi; Elsberger, Beatrix; Lovell, Lesley; Staff, Roger T; Masannat, Yazan A.
Afiliación
  • Macnab MF; Nuclear Medicine Department, Aberdeen Royal Infirmary, Aberdeen, Scotland, UK.
  • Slater G; The School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, Scotland, UK.
  • Fuller M; The School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, Scotland, UK; The Breast Unit, Aberdeen Royal Infirmary, Aberdeen, Scotland, UK.
  • Elsberger B; The School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, Scotland, UK; The Breast Unit, Aberdeen Royal Infirmary, Aberdeen, Scotland, UK.
  • Lovell L; Nuclear Medicine Department, Aberdeen Royal Infirmary, Aberdeen, Scotland, UK.
  • Staff RT; Nuclear Medicine Department, Aberdeen Royal Infirmary, Aberdeen, Scotland, UK.
  • Masannat YA; The School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, Scotland, UK; The Breast Unit, Aberdeen Royal Infirmary, Aberdeen, Scotland, UK. Electronic address: yazanmas@hotmail.com.
Clin Breast Cancer ; 22(5): e674-e679, 2022 07.
Article en En | MEDLINE | ID: mdl-35279407
BACKGROUND: Sentinel Lymph Node Biopsy (SLNB) is used to stage the axilla, but there is limited data in patients with prior ipsilateral breast cancer. This study compares redo-SLNB (reSLNB) and Axillary node sample (ANS) in this sub-cohort of patients. MATERIALS AND METHODS: This is a retrospective study looking at patients with a new ipsilateral primary or recurrence with history of breast-conserving surgery. Planned and performed surgery, patient demographics and previous treatments were recorded. Node positivity and success rate of reSLNB was analyzed. RESULTS: A total of 86 patients were identified that had mastectomy for ipsilateral recurrent disease with radiologically negative axilla. Out of the 48 that had reSLNB, 35(72.9%) were successful. Nineteen percent of the reSLNB had positive axillae and 20% of the ANS patients. reSLNB success rate was significantly lower amongst patients with previous axillary surgery (P = .014) and previous positive nodes(P = .001). CONCLUSION: reSLNB should be considered to restage the axilla in patients with previous history of ipsilateral cancer especially that there is growing evidence showing good identification rate.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Biopsia del Ganglio Linfático Centinela Tipo de estudio: Observational_studies / Prognostic_studies Límite: Female / Humans Idioma: En Revista: Clin Breast Cancer Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Biopsia del Ganglio Linfático Centinela Tipo de estudio: Observational_studies / Prognostic_studies Límite: Female / Humans Idioma: En Revista: Clin Breast Cancer Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos