Inhibition of temperature-sensitive TRPV3 channel by two natural isochlorogenic acid isomers for alleviation of dermatitis and chronic pruritus.

Qi, Hang; Shi, Yuntao; Wu, Han; Niu, Canyang; Sun, Xiaoying; Wang, KeWei

Qi, Hang; Shi, Yuntao; Wu, Han; Niu, Canyang; Sun, Xiaoying; Wang, KeWei.

Afiliación

Qi H; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao 266021, China.
Shi Y; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Wu H; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao 266021, China.
Niu C; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao 266021, China.
Sun X; Department of Pharmacology, School of Pharmacy, Qingdao University, Qingdao 266021, China.
Wang K; Institue of Innovative Drugs, Qingdao University, Qingdao 266021, China.

Acta Pharm Sin B ; 12(2): 723-734, 2022 Feb.

Article en En | MEDLINE | ID: mdl-35256942

Palabras clave

2-APB, 2-aminoethoxydiphenyl borate; AITC, allyl isothiocyanate; Chronic pruritus; DMEM, Dulbecco's modified Eagle's medium; Dermatitis; Dicaffeoylquinic acid; Ear swelling; Gate modifier; HEK293, human embryonic kidney 293; HaCaT, human immortalized nontumorigenic keratinocyte; IAA, isochlorogenic acid A; IAB, isochlorogenic acid B; OS, Olmsted syndrome; Olmsted syndrome; RR, ruthenium red; TRP, transient receptor potential; TRPV3

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies Idioma: En Revista: Acta Pharm Sin B Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

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