Your browser doesn't support javascript.
loading
Comparison of tissue biomarkers in arterial and vein (arteriovenous fistula) aneurysms.
Shahri, Jamal J; Saberianpour, Shirin; Bayegi, Saeed N.
Afiliación
  • Shahri JJ; Vascular and Endovascular Surgery Research Center, 37552Mashhad Medical University, Mashhad, Iran.
  • Saberianpour S; Vascular and Endovascular Surgery Research Center, 37552Mashhad Medical University, Mashhad, Iran.
  • Bayegi SN; Vascular and Endovascular Surgery Research Center, 37552Mashhad Medical University, Mashhad, Iran.
Phlebology ; 37(4): 289-295, 2022 May.
Article en En | MEDLINE | ID: mdl-35255762
INTRODUCTION AND OBJECTIVES: Aneurysms are distinguished by inflammation, matrix degradation, and apoptosis of smooth muscle cells. In this study, specialized aneurysms tissue markers including venous and arterial aneurysms were studied. MATERIAL AND METHODS: The present cross-sectional study was conducted throughout January-September 2021. Tissue samples were collected during surgery. Hematoxylin and eosin (H&E) stains, have been utilized to identify different aneurysm types and the morphologic alterations that serve as the foundation for aneurysm diagnosis. Measurement of collagen type III, IV, CCR2, metalloproteinase (2 and 13), and granzyme K was done by ELISA method. Results were presented as the mean ± standard deviation and analyzed by t tests (Graph Pad Prism 8.4.3.686). RESULTS: During the period from January to September 2021, 14 patients with peripheral venous and arterial aneurysms were referred to Alavi Vascular Surgery Hospital and underwent surgery. Of these, 10 patients were matched and remained available for study. The level of type 3 collagen was significantly reduced in arterial aneurysm compared to venous aneurysm (p < 0.05). Granzyme K in arterial aneurysm showed increase compared to venous aneurysm (p < 0.05). Metalloproteinase 2 in arterial aneurysms higher than venous aneurysm (p < 0.001). Metalloproteinase 13 in arterial aneurysm also showed increase compared to venous aneurysm (p < 0.05). CONCLUSION: Results of this study shows differences in the level of tissue biomarkers in arterial and vein (arteriovenous fistula) aneurysms.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fístula Arteriovenosa / Aneurisma Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Phlebology Asunto de la revista: ANGIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fístula Arteriovenosa / Aneurisma Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Phlebology Asunto de la revista: ANGIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido