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Rate versus rhythm control for atrial fibrillation: from AFFIRM to EAST-AFNET 4 - a paradigm shift.
Roman, Sherif; Patel, Kevin; Hana, David; Guice, Kenneth C; Patel, Jay; Stadnick, Christopher; Basta, Amir; Khouzam, Rami N.
Afiliación
  • Roman S; Department of Medicine, St Joseph's University Medical Center, NJ 07503, USA.
  • Patel K; Department of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
  • Hana D; Department of Medicine, Loyola University Medical Center/Trinity - Mercy Hospital, IL 60616, USA.
  • Guice KC; Department of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
  • Patel J; Department of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
  • Stadnick C; Department of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
  • Basta A; Department of Medicine, Ain Shams University, Cairo, 1181, Egypt.
  • Khouzam RN; Department of Medicine, Division of Cardiovascular Diseases, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Future Cardiol ; 18(4): 354-353, 2022 04.
Article en En | MEDLINE | ID: mdl-35255732
The clinical choice between rate or rhythm control therapies has been debated over the years. In 2002, the AFFIRM trial demonstrated that the rhythm-control strategy had no survival advantage over the rate-control strategy. Eighteen years later, EAST-AFNET 4 showed that the rhythm-control approach is better than rate control in reducing adverse cardiovascular outcomes in patients with a recent diagnosis of atrial fibrillation (AF). During the time between AFFIRM and EAST-AFNET 4, rhythm control understanding, specifically ablation, improved, while rate-control strategies remained the same possibly leading to the change in results seen in EAST-AFNET 4. This review seeks to evaluate the rate- and rhythm-control strategies, focusing on the important clinical trials in the past two decades. These trials have shown great advancement in AF management; however, the search for the best approach to controlling AF and minimizing the burden of symptoms is still a work in progress and needs further research.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fibrilación Atrial / Ablación por Catéter / Accidente Cerebrovascular Tipo de estudio: Diagnostic_studies / Etiology_studies Límite: Humans Idioma: En Revista: Future Cardiol Asunto de la revista: CARDIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fibrilación Atrial / Ablación por Catéter / Accidente Cerebrovascular Tipo de estudio: Diagnostic_studies / Etiology_studies Límite: Humans Idioma: En Revista: Future Cardiol Asunto de la revista: CARDIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido