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Comparison of frontal QRS-T angle in patients with schizophrenia and healthy volunteers.
Tekin, Atilla; Tanriverdi, Zülkif; Kapici, Yasar; Güc, Bulut; Karamustafalioglu, Oguz.
Afiliación
  • Tekin A; Adiyaman University, Faculty of Medicine, Psychiatry Department, Adiyaman, Turkey. Electronic address: md.atillatekin@gmail.com.
  • Tanriverdi Z; Harran University, Faculty of Medicine, Cardiology Department, Sanliurfa, Turkey. Electronic address: ztverdi@gmail.com.
  • Kapici Y; Adiyaman University, Faculty of Medicine, Psychiatry Department, Adiyaman, Turkey. Electronic address: dryasarkapici@gmail.com.
  • Güc B; Adiyaman University, Faculty of Medicine, Psychiatry Department, Adiyaman, Turkey. Electronic address: bulutguc88@gmail.com.
  • Karamustafalioglu O; Istanbul University-Cerrahpasa, Institue of Forensic Sciences, Istanbul, Turkey. Electronic address: oguzkaramustafa@gmail.com.
J Psychiatr Res ; 149: 76-82, 2022 05.
Article en En | MEDLINE | ID: mdl-35255386
Cardiovascular diseases are the most prominent cause of death in patients with schizophrenia. Frontal QRS-T (fQRS-T) angle is a novel marker of myocardial depolarization and repolarization heterogeneity. Recent studies have indicated that the fQRS-T angle is associated with some cardiovascular abnormalities. This study aimed to investigate the fQRS-T angle and its relationship with symptoms severity in patients with schizophrenia. One hundred-six patients with schizophrenia and sixty-four healthy controls were included in this study. fQRS-T angle and QT interval measurements were calculated for each participant from the automatic report of the 12-lead electrocardiography (ECG) device. The Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) and The Positive and Negative Syndrome Scale (PANSS) were performed on the patients with schizophrenia. Corrected QT (QTc) interval and fQRS-T angle were significantly higher in the patients with schizophrenia than healthy controls (p < 0.001 and p < 0.001, respectively). fQRS-T angle was positively correlated with age (r = 0.43), duration of disease (r = 0.37), and negative symptoms scores (r = 0.39). In linear regression analysis, the disease duration and negative symptom severity were the independent predictors of fQRS-T angle in patients with schizophrenia (t = 3.730, p = 0.003 and t = 2.257, p = 0.023, respectively). The fQRS-T angle may be an important ECG parameter to interpret cardiovascular disease risk in patients with schizophrenia.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esquizofrenia Tipo de estudio: Prognostic_studies / Qualitative_research Límite: Humans Idioma: En Revista: J Psychiatr Res Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esquizofrenia Tipo de estudio: Prognostic_studies / Qualitative_research Límite: Humans Idioma: En Revista: J Psychiatr Res Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido