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Transcriptomics analysis of cashmere fineness functional genes.
Qin, Yuting; Xu, Yanan; Zhang, Yu; Gu, Ming; Cai, Weidong; Bai, Zhixian; Zhang, Xinjiang; Chen, Rui; Sun, Yinggang; Wu, Yanzhi; Wang, Zeying.
Afiliación
  • Qin Y; College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Xu Y; College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Zhang Y; College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Gu M; College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Cai W; College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Bai Z; College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Zhang X; College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Chen R; College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Sun Y; College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Wu Y; College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Wang Z; College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
Anim Biotechnol ; 34(4): 1583-1593, 2023 Nov.
Article en En | MEDLINE | ID: mdl-35253626
Liaoning cashmere goat (LCG) is a famous cashmere goat breed in China. Cashmere fineness, as an important index to evaluate cashmere quality, is also one of the problems to be improved for Liaoning cashmere goats. Transcriptome studies all mRNA transcribed by a specific tissue or cell in a certain period. It is a key link in the study of gene expression regulation. It plays an important role in the analysis of biological growth and disease. Transcriptome is spatio-temporal specific, that is, gene expression varies in different tissues or at different times. Three coarser and three fine LCG skin samples were sequenced by RNA-seq technology, and a total of 427 differentially expressed genes were obtained, including 291 up-regulated genes and 136 down-regulated genes. In the experiment, we screened out 16 genes that had significant differences in the expression of coarse and fine cashmere of Liaoning cashmere goats, so it was inferred that these 16 genes might have regulatory effects on cashmere fineness. Moreover, GO gene set enrichment analysis revealed that differential genes mainly consist of immune response, MHC protein complex, Heme binding and other pathways. KEGG analysis showed that transplant-versus-host disease and allograft rejection were the main pathways of differential genes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regulación de la Expresión Génica / Transcriptoma Límite: Animals Idioma: En Revista: Anim Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regulación de la Expresión Génica / Transcriptoma Límite: Animals Idioma: En Revista: Anim Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido