The association between serum cystatin C and residual renal function in peritoneal dialysis patients.
Ther Apher Dial
; 26(6): 1241-1246, 2022 Dec.
Article
en En
| MEDLINE
| ID: mdl-35253373
INTRODUCTION: This study evaluated the association between serum cystatin C and residual renal function (RRF) in peritoneal dialysis (PD) patients. METHODS: The ability of cystatin C to predict RRF was assessed. Multivariate linear regression analysis was conducted to measure the impact of particular factors on serum cystatin C levels. RESULTS: The study included 141 PD patients. Serum creatinine and cystatin C were negatively correlated with RRF (p < 0.05). Receiver operating characteristic (ROC) curves showed that serum creatinine and cystatin C could both predict RRF status (p < 0.05), but serum cystatin C had a larger area AUC than creatinine (0.893 vs. 0.757, respectively), p < 0.001). Multiple linear regression analysis revealed that RRF Kt/V and Ccr were independent factors affecting serum cystatin C levels (p < 0.001). CONCLUSION: Serum cystatin C levels were closely associated with RRF in PD patients and could reliably predict RRF status. Serum cystatin C levels were determined by RRF, not by PD.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Diálisis Peritoneal
/
Fallo Renal Crónico
Tipo de estudio:
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Ther Apher Dial
Asunto de la revista:
HEMATOLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
Australia