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[Effects of diet on the gut microbiome in patients with depression]. / Vliyanie diety na mikrobiom kishechnika u patsientov s depressiei.
Zorkina, Ya A; Syunyakov, T S; Abramova, O V; Yunes, R A; Averina, O V; Kovtun, A S; Angelova, I Yu; Khobta, E B; Susloparova, D A; Pavlichenko, A V; Karpenko, O A; Andreyuk, D S; Tovmasyan, A S; Danilenko, V N; Gurina, O I; Kostyuk, G P; Morozova, A Yu.
Afiliación
  • Zorkina YA; Serbsky National Research Institute of Psychiatry and Narcology, Moscow, Russia.
  • Syunyakov TS; Mental Health Clinic No. 1 named after N.A. Alexeev, Moscow, Russia.
  • Abramova OV; Mental Health Clinic No. 1 named after N.A. Alexeev, Moscow, Russia.
  • Yunes RA; Serbsky National Research Institute of Psychiatry and Narcology, Moscow, Russia.
  • Averina OV; Mental Health Clinic No. 1 named after N.A. Alexeev, Moscow, Russia.
  • Kovtun AS; Vavilov Institute of General Genetics RAS, Moscow, Russia.
  • Angelova IY; Vavilov Institute of General Genetics RAS, Moscow, Russia.
  • Khobta EB; Vavilov Institute of General Genetics RAS, Moscow, Russia.
  • Susloparova DA; Skoltech Center of Life Sciences, Moscow, Russia.
  • Pavlichenko AV; Moscow Institute of Physics and Technology (National Research University), Moscow, Russia.
  • Karpenko OA; Mental Health Clinic No. 1 named after N.A. Alexeev, Moscow, Russia.
  • Andreyuk DS; Mental Health Clinic No. 1 named after N.A. Alexeev, Moscow, Russia.
  • Tovmasyan AS; Mental Health Clinic No. 1 named after N.A. Alexeev, Moscow, Russia.
  • Danilenko VN; Mental Health Clinic No. 1 named after N.A. Alexeev, Moscow, Russia.
  • Gurina OI; Mental Health Clinic No. 1 named after N.A. Alexeev, Moscow, Russia.
  • Kostyuk GP; Sverzhevsky Research Clinical Institute of Otorhinolaryngology, Moscow, Russia.
  • Morozova AY; Vavilov Institute of General Genetics RAS, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova ; 122(1. Vyp. 2): 59-64, 2022.
Article en Ru | MEDLINE | ID: mdl-35238513
OBJECTIVE: To investigate the effects of diet on the gut microbiota and to assess the relationship of these factors with depression. MATERIAL AND METHODS: Microorganisms that predominate in depressed patients were identified and associations of the identified organisms with the patients' diet were performed. Fourteen depressed patients and 14 healthy volunteers with the same socio-demographic parameters were included in the study. The Hamilton Depression Scale, Generalized Anxiety Disorder Questionnaire, and the Center for Epidemiologic Studies Questionnaire were used. RESULTS: Erysipelatoclostridium and Clostridium innocuum species were 11.3 and 14.4 times higher in depressed patients compared with healthy controls. Fusicatenibacter saccharivorans, Faecalibacterium prausnitzii and Roseburia faecis species, as well as members of the genus Roseburia were statistically significantly more abundant in the healthy volunteers group (6.5, 2.14, 8.75 and 5.2 times more frequently compared to patients). The presence of these microorganisms was correlated with dietary components. CONCLUSION: Our study revealed groups of microorganisms that differ in healthy volunteers and depressed patients. The association of these microorganisms with the diet was shown, which partially confirmed the influence of a «healthy diet¼ on the development of depressive disorders.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microbioma Gastrointestinal Tipo de estudio: Prognostic_studies Límite: Humans Idioma: Ru Revista: Zh Nevrol Psikhiatr Im S S Korsakova Asunto de la revista: NEUROLOGIA / PSIQUIATRIA Año: 2022 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Rusia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microbioma Gastrointestinal Tipo de estudio: Prognostic_studies Límite: Humans Idioma: Ru Revista: Zh Nevrol Psikhiatr Im S S Korsakova Asunto de la revista: NEUROLOGIA / PSIQUIATRIA Año: 2022 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Rusia