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The fine-needle aspiration cytology and clinical findings of Kikuchi-Fujimoto disease in pediatric patients: a retrospective clinical study.
Naoi, Yuto; Tachibana, Tomoyasu; Wani, Yoji; Hotta, Machiko; Haruna, Katsuya; Komatsubara, Yasutoshi; Kuroda, Kazunori; Fushimi, Soichiro; Nagatani, Tami; Kataoka, Yuko; Nishizaki, Kazunori; Sato, Yasuharu; Ando, Mizuo.
Afiliación
  • Naoi Y; Department of Otolaryngology Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama City, Japan.
  • Tachibana T; Department of Otolaryngology, Japanese Red Cross Society Himeji Hospital, Himeji City, Japan.
  • Wani Y; Department of Pathology, Japanese Red Cross Society Himeji Hospital, Himeji City, Japan.
  • Hotta M; Department of Pathology, Japanese Red Cross Society Himeji Hospital, Himeji City, Japan.
  • Haruna K; Department of Inspection Technology, Japanese Red Cross Society Himeji Hospital, Himeji City, Japan.
  • Komatsubara Y; Department of Otolaryngology, Japanese Red Cross Society Himeji Hospital, Himeji City, Japan.
  • Kuroda K; Department of Otolaryngology, Japanese Red Cross Society Himeji Hospital, Himeji City, Japan.
  • Fushimi S; Department of Pathology, Japanese Red Cross Society Himeji Hospital, Himeji City, Japan.
  • Nagatani T; Department of Inspection Technology, Japanese Red Cross Society Himeji Hospital, Himeji City, Japan.
  • Kataoka Y; Department of Otolaryngology Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama City, Japan.
  • Nishizaki K; Department of Otolaryngology Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama City, Japan.
  • Sato Y; Department of Clinical Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama City, Japan.
  • Ando M; Department of Otolaryngology Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama City, Japan.
Acta Otolaryngol ; 142(3-4): 340-344, 2022.
Article en En | MEDLINE | ID: mdl-35235442
BACKGROUND: Histological evaluation of lymph node is crucial for the definitive diagnosis of Kikuchi-Fujimoto disease (KFD). However, lymph node biopsy under local anesthesia is often difficult in pediatric patients. OBJECTIVES: We evaluated cytological findings for pediatric patients with prolonged cervical lymphadenitis clinically suggestive of KFD and investigated the clinical characteristics of patients diagnosed with KFD by fine-needle aspiration cytology (FNAC). METHODS: This retrospective clinical study included 58 Japanese pediatric patients with cervical lymphadenitis who underwent FNAC. RESULTS: Cytological diagnosis was KFD for 22 and suspicion of KFD for 11 patients. The remaining 25 patients were diagnosed with non-specific lymphadenitis (NSL). Tenderness was independently associated with a higher frequency of both KFD in narrow and broad senses, compared with NSL (p = .009; p = .038). The percentage of patients who underwent FNAC within 28 days from symptom onset tended to be higher among patients with KFD in a narrow sense than those with NSL (p = .052). CONCLUSION: This study indicated that the period from symptom onset to FNAC (<28 days) and the symptom of tenderness were associated with the cytological diagnosis of KFD.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfadenitis Necrotizante Histiocítica / Linfadenitis Tipo de estudio: Diagnostic_studies / Observational_studies / Risk_factors_studies Límite: Child / Humans Idioma: En Revista: Acta Otolaryngol Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfadenitis Necrotizante Histiocítica / Linfadenitis Tipo de estudio: Diagnostic_studies / Observational_studies / Risk_factors_studies Límite: Child / Humans Idioma: En Revista: Acta Otolaryngol Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido