Your browser doesn't support javascript.
loading
Flow adjusted transmitral pressure gradient as a modified indicator of functional mitral stenosis after repair for degenerative mitral regurgitation.
Hiraoka, Arudo; Hayashida, Akihiro; Totusgawa, Toshinori; Toki, Misako; Chikazawa, Genta; Yoshitaka, Hidenori; Sakaguchi, Taichi.
Afiliación
  • Hiraoka A; Department of Cardiovascular Surgery, The Sakakibara Heart Institute of Okayama, Okayama, Japan.
  • Hayashida A; Department of Cardiology, The Sakakibara Heart Institute of Okayama, Okayama, Japan.
  • Totusgawa T; Department of Cardiovascular Surgery, The Sakakibara Heart Institute of Okayama, Okayama, Japan.
  • Toki M; Department of Clinical Laboratory, The Sakakibara Heart Institute of Okayama, Okayama, Japan.
  • Chikazawa G; Department of Cardiovascular Surgery, The Sakakibara Heart Institute of Okayama, Okayama, Japan.
  • Yoshitaka H; Department of Cardiovascular Surgery, The Sakakibara Heart Institute of Okayama, Okayama, Japan.
  • Sakaguchi T; Department of Cardiovascular Surgery, The Sakakibara Heart Institute of Okayama, Okayama, Japan.
J Card Surg ; 37(7): 1827-1834, 2022 Jul.
Article en En | MEDLINE | ID: mdl-35234318
BACKGROUND AND AIM: After repair of degenerative mitral regurgitation (DMR), the focus is on functional mitral stenosis (FMS) when there is a decline of mitral hemodynamics. Yet, the clinical impacts and a standardized definition are still undecided. Since common mitral hemodynamic parameters are influenced by transmitral flow, the aim of this study is to seek the impact of flow adjusted transmitral pressure gradient (TMPG) by left ventricular stroke volume (LVSV) on the midterm outcomes. METHODS: Three hundred one patients who had undergone isolated mitral valve repair for degenerative lesions with annuloplasty prosthesis between October 2012 and June 2019 were included. Postoperative adverse events occurred in 20 patients (6.6%). Flow adjusted TMPG was defined as TMPG/LVSV. RESULTS: Common mitral hemodynamic parameters were not associated with adverse events. By multivariable analysis, patients' age, left ventricular ejection fraction (LVEF) and mean TMPG/LVSV were isolated as independent predictors (adjusted hazard ratio: 1.05, 0.95, and 1.16; p = .037, .005, and .035). Flow adjusted TMPG was significantly higher in the full ring group compared to the partial band group (0.051 mmHg/ml, [0.038-0.068] vs. 0.041 mmHg/ml, [0.031-0.056]; p < .001) and had a significantly negative correlation with the size of the annuloplasty prosthesis (r = -0.37, p < .001). CONCLUSIONS: Conventional mitral hemodynamic parameters were not associated with adverse cardiac events after repair for DMR. Adjustment by flow has a potential to advance pressure gradient to a more sensitive indicator of FMS associated with clinical outcomes.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Implantación de Prótesis de Válvulas Cardíacas / Anuloplastia de la Válvula Mitral / Insuficiencia de la Válvula Mitral / Estenosis de la Válvula Mitral Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies Límite: Humans Idioma: En Revista: J Card Surg Asunto de la revista: CARDIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Implantación de Prótesis de Válvulas Cardíacas / Anuloplastia de la Válvula Mitral / Insuficiencia de la Válvula Mitral / Estenosis de la Válvula Mitral Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies Límite: Humans Idioma: En Revista: J Card Surg Asunto de la revista: CARDIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos