Membrane tethering of CreER decreases uninduced cell labeling and cytotoxicity while maintaining recombination efficiency.

Chen, Mianqiao; Tian, Xiong; Xu, Liqun; Wu, Ruolan; He, Haoming; Zhu, Haibao; Xu, Wencan; Wei, Chi-Ju

Chen, Mianqiao; Tian, Xiong; Xu, Liqun; Wu, Ruolan; He, Haoming; Zhu, Haibao; Xu, Wencan; Wei, Chi-Ju.

Afiliación

Chen M; Guangdong Provincial Key Laboratory of Marine Biotechnology, Institute of Marine Sciences, Shantou University, Shantou, Guangdong 515063, China.
Tian X; Guangdong Provincial Key Laboratory of Marine Biotechnology, Institute of Marine Sciences, Shantou University, Shantou, Guangdong 515063, China.
Xu L; Guangdong Provincial Key Laboratory of Marine Biotechnology, Institute of Marine Sciences, Shantou University, Shantou, Guangdong 515063, China.
Wu R; Guangdong Provincial Key Laboratory of Marine Biotechnology, Institute of Marine Sciences, Shantou University, Shantou, Guangdong 515063, China.
He H; Guangdong Provincial Key Laboratory of Marine Biotechnology, Institute of Marine Sciences, Shantou University, Shantou, Guangdong 515063, China.
Zhu H; Guangdong Provincial Key Laboratory of Marine Biotechnology, Institute of Marine Sciences, Shantou University, Shantou, Guangdong 515063, China.
Xu W; Department of Endocrinology, the First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China.
Wei CJ; Guangdong Provincial Key Laboratory of Marine Biotechnology, Institute of Marine Sciences, Shantou University, Shantou, Guangdong 515063, China.

Mol Ther Nucleic Acids ; 27: 1078-1091, 2022 Mar 08.

Article en En | MEDLINE | ID: mdl-35228901

Palabras clave

FKBP; HSP90; TEV protease; cell labeling leakage; chemically induced dimerization; membrane localized CreER

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Mol Ther Nucleic Acids Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google