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The ChAdOx1 vectored vaccine, AZD2816, induces strong immunogenicity against SARS-CoV-2 beta (B.1.351) and other variants of concern in preclinical studies.
Spencer, Alexandra J; Morris, Susan; Ulaszewska, Marta; Powers, Claire; Kailath, Reshma; Bissett, Cameron; Truby, Adam; Thakur, Nazia; Newman, Joseph; Allen, Elizabeth R; Rudiansyah, Indra; Liu, Chang; Dejnirattisai, Wanwisa; Mongkolsapaya, Juthathip; Davies, Hannah; Donnellan, Francesca R; Pulido, David; Peacock, Thomas P; Barclay, Wendy S; Bright, Helen; Ren, Kuishu; Screaton, Gavin; McTamney, Patrick; Bailey, Dalan; Gilbert, Sarah C; Lambe, Teresa.
Afiliación
  • Spencer AJ; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom. Electronic address: alex.spencer@ndm.ox.ac.uk.
  • Morris S; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom.
  • Ulaszewska M; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom.
  • Powers C; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom.
  • Kailath R; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom.
  • Bissett C; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom.
  • Truby A; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom.
  • Thakur N; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom; The Pirbright Institute, Woking, Surrey, United Kingdom.
  • Newman J; The Pirbright Institute, Woking, Surrey, United Kingdom.
  • Allen ER; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom.
  • Rudiansyah I; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom.
  • Liu C; The Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, United Kingdom; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, United Kingdom.
  • Dejnirattisai W; The Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, United Kingdom.
  • Mongkolsapaya J; The Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, United Kingdom.
  • Davies H; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom.
  • Donnellan FR; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom.
  • Pulido D; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom.
  • Peacock TP; Department of Infectious Disease, Imperial College London, United Kingdom.
  • Barclay WS; Department of Infectious Disease, Imperial College London, United Kingdom.
  • Bright H; Virology and Vaccine Discovery, Microbial Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD United States.
  • Ren K; Virology and Vaccine Discovery, Microbial Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD United States.
  • Screaton G; The Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, United Kingdom.
  • McTamney P; Virology and Vaccine Discovery, Microbial Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD United States.
  • Bailey D; The Pirbright Institute, Woking, Surrey, United Kingdom.
  • Gilbert SC; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom.
  • Lambe T; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, United Kingdom.
EBioMedicine ; 77: 103902, 2022 Mar.
Article en En | MEDLINE | ID: mdl-35228013
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: SARS-CoV-2 / COVID-19 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: EBioMedicine Año: 2022 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: SARS-CoV-2 / COVID-19 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: EBioMedicine Año: 2022 Tipo del documento: Article Pais de publicación: Países Bajos