Your browser doesn't support javascript.
loading
Dispersion of SARS-CoV-2 in air surrounding COVID-19-infected individuals with mild symptoms.
Gohli, Jostein; Anderson, Ane Marie; Brantsaeter, Arne Broch; Bøifot, Kari Oline; Grub, Carola; Hadley, Cathrine Lund; Lind, Andreas; Pettersen, Ellen Susanne; Søraas, Arne Vasli Lund; Dybwad, Marius.
Afiliación
  • Gohli J; Norwegian Defence Research Establishment, Kjeller, Norway.
  • Anderson AM; Oslo University Hospital, Nydalen, Norway.
  • Brantsaeter AB; Department of Infectious Diseases, Norwegian National Unit for CBRNE Medicine, Oslo University Hospital, Nydalen, Norway.
  • Bøifot KO; Norwegian Defence Research Establishment, Kjeller, Norway.
  • Grub C; Department of Analytics, Environmental & Forensic Sciences, King's College London, London, UK.
  • Hadley CL; Institute of microbiology, Norwegian Armed Forces Joint Medical Services, Kjeller, Norway.
  • Lind A; Oslo University Hospital, Nydalen, Norway.
  • Pettersen ES; AGE LABS AS, Oslo, Norway.
  • Søraas AVL; Oslo University Hospital, Nydalen, Norway.
  • Dybwad M; Oslo University Hospital, Nydalen, Norway.
Indoor Air ; 32(2): e13001, 2022 02.
Article en En | MEDLINE | ID: mdl-35225394
Since the beginning of the pandemic, the transmission modes of SARS-CoV-2-particularly the role of aerosol transmission-have been much debated. Accumulating evidence suggests that SARS-CoV-2 can be transmitted by aerosols, and not only via larger respiratory droplets. In this study, we quantified SARS-CoV-2 in air surrounding 14 test subjects in a controlled setting. All subjects had SARS-CoV-2 infection confirmed by a recent positive PCR test and had mild symptoms when included in the study. RT-PCR and cell culture analyses were performed on air samples collected at distances of one, two, and four meters from test subjects. Oronasopharyngeal samples were taken from consenting test subjects and analyzed by RT-PCR. Additionally, total aerosol particles were quantified during air sampling trials. Air viral concentrations at one-meter distance were significantly correlated with both viral loads in the upper airways, mild coughing, and fever. One sample collected at four-meter distance was RT-PCR positive. No samples were successfully cultured. The results reported here have potential application for SARS-CoV-2 detection and monitoring schemes, and for increasing our understanding of SARS-CoV-2 transmission dynamics. Practical implications. In this study, quantification of SARS-CoV-2 in air was performed around infected persons with mild symptoms. Such persons may go longer before they are diagnosed and may thus be a disproportionately important epidemiological group. By correlating viral concentrations in air with behavior and symptoms, we identify potential risk factors for viral dissemination in indoor environments. We also show that quantification of total aerosol particles is not a useful strategy for monitoring SARS-CoV-2 in indoor environments.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Contaminación del Aire Interior / Microbiología del Aire / SARS-CoV-2 / COVID-19 Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Indoor Air Asunto de la revista: SAUDE AMBIENTAL Año: 2022 Tipo del documento: Article País de afiliación: Noruega Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Contaminación del Aire Interior / Microbiología del Aire / SARS-CoV-2 / COVID-19 Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Indoor Air Asunto de la revista: SAUDE AMBIENTAL Año: 2022 Tipo del documento: Article País de afiliación: Noruega Pais de publicación: Reino Unido