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A score years' update in the synthesis and biological evaluation of medicinally important 2-pyridones.
Sangwan, Sarita; Yadav, Neelam; Kumar, Ravi; Chauhan, Sonu; Dhanda, Vidhi; Walia, Pooja; Duhan, Anil.
Afiliación
  • Sangwan S; Department of Chemistry, Chaudhary Charan Singh Haryana Agricultural University, Hisar, Haryana, 125004, India. Electronic address: chemsarita2924@gmail.com.
  • Yadav N; Department of Chemistry, Chaudhary Charan Singh Haryana Agricultural University, Hisar, Haryana, 125004, India. Electronic address: raon5577@gmail.com.
  • Kumar R; Department of Chemistry, Chaudhary Charan Singh Haryana Agricultural University, Hisar, Haryana, 125004, India. Electronic address: ravibeniwal@hau.ac.in.
  • Chauhan S; Department of Chemistry, Chaudhary Charan Singh Haryana Agricultural University, Hisar, Haryana, 125004, India.
  • Dhanda V; Department of Chemistry, Chaudhary Charan Singh Haryana Agricultural University, Hisar, Haryana, 125004, India.
  • Walia P; Department of Chemistry, Chaudhary Charan Singh Haryana Agricultural University, Hisar, Haryana, 125004, India.
  • Duhan A; Department of Chemistry, Chaudhary Charan Singh Haryana Agricultural University, Hisar, Haryana, 125004, India.
Eur J Med Chem ; 232: 114199, 2022 Mar 15.
Article en En | MEDLINE | ID: mdl-35219150
2-Pyridone core structure has attracted much attention due to its abundance in natural products of biological importance. 2-Pyridone derivatives display diverse biological activities. From being antimicrobial, antimalarial, antitumor, cardiotonic and anti-fibrotic agents to the induction of neurite outgrowth, they affect many biological processes. They find significant role in medicines, agriculture, pharmacophore designing and are also used as synthones for other heterocyclic compounds. Therefore, the main purpose of this review is to assess the biological pursuits of 2-pyridone compounds. In addition, this review presents the overview of synthesis of medicinally active 2-pyridones along with their biological activity done in the past two decades.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos Heterocíclicos / Antiinfecciosos / Antimaláricos Idioma: En Revista: Eur J Med Chem Año: 2022 Tipo del documento: Article Pais de publicación: Francia
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos Heterocíclicos / Antiinfecciosos / Antimaláricos Idioma: En Revista: Eur J Med Chem Año: 2022 Tipo del documento: Article Pais de publicación: Francia