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The In Vivo Quantitative Assessment of the Effectiveness of Low-Dose Photodynamic Therapy on Wound Healing Using Optical Coherence Tomography.
Zuhayri, Hala; Nikolaev, Viktor V; Lepekhina, Tatiana B; Sandykova, Ekaterina A; Krivova, Natalya A; Kistenev, Yury V.
Afiliación
  • Zuhayri H; Laboratory of Laser Molecular Imaging and Machine Learning, Tomsk State University, Lenin Ave. 36, 634050 Tomsk, Russia.
  • Nikolaev VV; Laboratory of Laser Molecular Imaging and Machine Learning, Tomsk State University, Lenin Ave. 36, 634050 Tomsk, Russia.
  • Lepekhina TB; Laboratory of Laser Molecular Imaging and Machine Learning, Tomsk State University, Lenin Ave. 36, 634050 Tomsk, Russia.
  • Sandykova EA; Laboratory of Laser Molecular Imaging and Machine Learning, Tomsk State University, Lenin Ave. 36, 634050 Tomsk, Russia.
  • Krivova NA; Laboratory of Laser Molecular Imaging and Machine Learning, Tomsk State University, Lenin Ave. 36, 634050 Tomsk, Russia.
  • Kistenev YV; Laboratory of Laser Molecular Imaging and Machine Learning, Tomsk State University, Lenin Ave. 36, 634050 Tomsk, Russia.
Pharmaceutics ; 14(2)2022 Feb 11.
Article en En | MEDLINE | ID: mdl-35214134
The effect of low-dose photodynamic therapy on in vivo wound healing was investigated using optical coherence tomography. This work aims to develop an approach to quantitative assessment of the wound's state during wound healing including the effect of low-dose photodynamic therapy using topical application of two different photosensitizers, 5-aminolevulinic acid and methylene blue, and two laser doses of 1 J/cm2 and 4 J/cm2. It was concluded that the laser dose of 4 J/cm2 was better compared to 1 J/cm2 and allowed the wound healing process to accelerate.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pharmaceutics Año: 2022 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pharmaceutics Año: 2022 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Suiza