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Postoperative mortality in the COVID-positive hip fracture patient, a systematic review and meta-analysis.
Isla, Alexander; Landy, David; Teasdall, Robert; Mittwede, Peter; Albano, Ashley; Tornetta, Paul; Bhandari, Mohit; Aneja, Arun.
Afiliación
  • Isla A; Department of Orthopaedic Surgery, University of Kentucky, 740 South Limestone, Suite K413, Lexington, KY, 40536-0284, USA.
  • Landy D; Department of Orthopaedic Surgery, University of Kentucky, 740 South Limestone, Suite K413, Lexington, KY, 40536-0284, USA.
  • Teasdall R; Department of Orthopaedic Surgery, University of Kentucky, 740 South Limestone, Suite K413, Lexington, KY, 40536-0284, USA.
  • Mittwede P; University of Pittsburgh, Pittsburgh, PA, USA.
  • Albano A; Department of Orthopaedic Surgery, University of Kentucky, 740 South Limestone, Suite K413, Lexington, KY, 40536-0284, USA.
  • Tornetta P; Boston University Medical Center, Boston, MA, USA.
  • Bhandari M; McMaster University, Hamilton, ON, Canada.
  • Aneja A; Department of Orthopaedic Surgery, University of Kentucky, 740 South Limestone, Suite K413, Lexington, KY, 40536-0284, USA. aan247@uky.edu.
Eur J Orthop Surg Traumatol ; 33(4): 927-935, 2023 May.
Article en En | MEDLINE | ID: mdl-35195751
PURPOSE: The extent to which concomitant COVID-19 infection increases short-term mortality following hip fracture is not fully understood. A systemic review and meta-analysis of COVID-19 positive hip fracture patients (CPHFPs) undergoing surgery was conducted to explore the association of COVID-19 with short-term mortality. METHODS: Review of the literature identified reports of short-term 30-day postoperative mortality in CPHFPs. For studies including a contemporary control group of COVID-19 negative patients, odds ratios of the association between COVID-19 infection and short-term mortality were calculated. Short-term mortality and the association between COVID-19 infection and short-term mortality were meta-analyzed and stratified by hospital screening type using random effects models. RESULTS: Seventeen reports were identified. The short-term mortality in CPHFPs was 34% (95% C.I., 30-39%). Short-term mortality differed slightly across studies that screened all patients, 30% (95% C.I., 22-39%), compared to studies that conditionally screened patients, 36% (95% C.I., 31-42%), (P = 0.22). The association between COVID-19 infection and short-term mortality produced an odds ratio of 7.16 (95% C.I., 4.99-10.27), and this was lower for studies that screened all patients, 4.08 (95% C.I., 2.31-7.22), compared to studies that conditionally screened patients, 8.32 (95% C.I., 5.68-12.18), (P = 0.04). CONCLUSION: CPHFPs have a short-term mortality rate of 34%. The odds ratio of short-term mortality was significantly higher in studies that screened patients conditionally than in studies that screened all hip fracture patients. This suggests mortality prognostication should consider how COVID-19 infection was identified as asymptomatic patients may fare slightly better.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 / Fracturas de Cadera Tipo de estudio: Prognostic_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Eur J Orthop Surg Traumatol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 / Fracturas de Cadera Tipo de estudio: Prognostic_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Eur J Orthop Surg Traumatol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Francia