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Effect of Oat (Avena sativa L.) Consumption on Lipid Profile With Focus on Triglycerides and High-density Lipoprotein Cholesterol (HDL-C): An Updated Systematic Review.
Amerizadeh, Atefeh; Ghaheh, Hooria Seyedhosseini; Vaseghi, Golnaz; Farajzadegan, Ziba; Asgary, Sedigheh.
Afiliación
  • Amerizadeh A; Department of Pharmaceutical Sciences, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Ghaheh HS; Department of Pharmaceutical Biotechnology, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Vaseghi G; Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Farajzadegan Z; Community Medicine Department, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Asgary S; Department of Pharmaceutical Sciences, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address: sedighehasgary@gmail.com.
Curr Probl Cardiol ; 48(7): 101153, 2023 Jul.
Article en En | MEDLINE | ID: mdl-35192870
Hypercholesterolemia is a significant risk factor for heart disease. The soluble fiber in oat (Avena sativa L.), beta-glucan has been shown to significantly lower serum total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) levels but not triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C) according to previous studies, reviews, and meta-analyses. However, the effect of oat consumption on the TG and HDL-C is controversial and has not been expanded enough. We did this review study to find out about the effect of oat on lipid profile especially TG and HDL-C more specifically and meticulously with their details. After searching PubMed, Web of Science, and Google scholar we included 17 studies in our review. Our results similar to other reviews showed that oat reduced the TC, VLDL, and LDL-C more significantly than TG. Of 17 included studies 6 studies reported reduction of TG level, and only 1 study reported HDL-C improvement followed by oat consumption. A more detailed review of studies that reported positive effects of oat/ beta-glucan consumption on TG showed that in healthy people with normal lipid profile oat intake might reduce TG effectively and also in overweight people/those with diabetes or metabolic syndrome if a higher amount of oat or/and longer duration applied. Consuming oat in conjunction with calorie-reducing diets or using it with DHA can cause a significant TG reduction. It may be concluded that, in addition to lowering TC and LDL-C, a considerable improvement in TG or HDL-C can be accomplished by adjusting factors such as oat consumption dose or consumption duration or utilizing oat in conjunction with a proper diet program. To conclude, more research on this topic is required.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Beta-Glucanos / Cardiopatías Tipo de estudio: Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Curr Probl Cardiol Año: 2023 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Beta-Glucanos / Cardiopatías Tipo de estudio: Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Curr Probl Cardiol Año: 2023 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Países Bajos