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Low Perinatal Androgens Predict Recalled Childhood Gender Nonconformity in Men.
Shirazi, Talia N; Self, Heather; Rosenfield, Kevin A; Dawood, Khytam; Welling, Lisa L M; Cárdenas, Rodrigo; Bailey, J Michael; Balasubramanian, Ravikumar; Delaney, Angela; Breedlove, S Marc; Puts, David A.
Afiliación
  • Shirazi TN; Department of Anthropology, The Pennsylvania State University.
  • Self H; Department of Anthropology, The Pennsylvania State University.
  • Rosenfield KA; Department of Anthropology, The Pennsylvania State University.
  • Dawood K; Department of Psychology, The Pennsylvania State University.
  • Welling LLM; Department of Psychology, Oakland University.
  • Cárdenas R; Department of Psychology, The Pennsylvania State University.
  • Bailey JM; Department of Psychology, Northwestern University.
  • Balasubramanian R; Reproductive Endocrine Unit, Massachusetts General Hospital, Boston, Massachusetts.
  • Delaney A; Reproductive Physiology and Pathophysiology Group, National Institutes of Health, Bethesda, Maryland.
  • Breedlove SM; Department of Neuroscience, Michigan State University.
  • Puts DA; Department of Anthropology, The Pennsylvania State University.
Psychol Sci ; 33(3): 343-353, 2022 03.
Article en En | MEDLINE | ID: mdl-35191784
The contributions of gonadal hormones to the development of human behavioral sex differences are subjects of intense scientific and social interest. Isolated gonadotropin-releasing-hormone deficiency (IGD) is a rare endocrine disorder that can reveal a possible role of early gonadal hormones. IGD is characterized by low or absent gonadal hormone production after the first trimester of gestation, but external genitalia and hence gender of rearing are concordant with chromosomal and gonadal sex. We investigated recalled childhood gender nonconformity in men (n = 65) and women (n = 32) with IGD and typically developing men (n = 463) and women (n = 1,207). Men with IGD showed elevated childhood gender nonconformity, particularly if they also reported undescended testes at birth, a marker of low perinatal androgens. Women with IGD did not differ from typically developing women. These results indicate that early androgen exposure after the first trimester contributes to male-typical gender-role behaviors in childhood.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Identidad de Género / Andrógenos Tipo de estudio: Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Límite: Female / Humans / Male / Newborn Idioma: En Revista: Psychol Sci Asunto de la revista: PSICOLOGIA Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Identidad de Género / Andrógenos Tipo de estudio: Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Límite: Female / Humans / Male / Newborn Idioma: En Revista: Psychol Sci Asunto de la revista: PSICOLOGIA Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos