D,L-Methadone enhances the cytotoxic activity of standard chemotherapeutic agents on pediatric rhabdomyosarcoma.

Urla, Cristian; Corteletti, Irene; Raible, Ann-Sophie; Handgretinger, Rupert; Fuchs, Jörg; Warmann, Steven W; Schmid, Evi

Urla, Cristian; Corteletti, Irene; Raible, Ann-Sophie; Handgretinger, Rupert; Fuchs, Jörg; Warmann, Steven W; Schmid, Evi.

Afiliación

Urla C; Department of Pediatric Surgery and Pediatric Urology, University Children's Hospital of Tuebingen, Hoppe-Seyler-Str. 3, 72076, Tuebingen, Germany.
Corteletti I; Department of Pediatric Surgery and Pediatric Urology, University Children's Hospital of Tuebingen, Hoppe-Seyler-Str. 3, 72076, Tuebingen, Germany.
Raible AS; Department of Molecular Medicine, University of Padova, Via Gabelli 63, 35121, Padova, Italy.
Handgretinger R; Department of Pediatric Surgery and Pediatric Urology, University Children's Hospital of Tuebingen, Hoppe-Seyler-Str. 3, 72076, Tuebingen, Germany.
Fuchs J; Department of Pediatric Hematology and Oncology, University Children's Hospital of Tuebingen, Hoppe-Seyler-Str. 1, 72076, Tuebingen, Germany.
Warmann SW; Department of Pediatric Hematology and Oncology, University Children's Hospital of Tuebingen, Hoppe-Seyler-Str. 1, 72076, Tuebingen, Germany.
Schmid E; Department of Pediatric Surgery and Pediatric Urology, University Children's Hospital of Tuebingen, Hoppe-Seyler-Str. 3, 72076, Tuebingen, Germany.

J Cancer Res Clin Oncol ; 148(6): 1337-1350, 2022 Jun.

Article en En | MEDLINE | ID: mdl-35182225

Asunto(s)

Antineoplásicos; Rabdomiosarcoma Embrionario; Rabdomiosarcoma; Antineoplásicos/farmacología; Antineoplásicos/uso terapéutico; Apoptosis; Carboplatino/farmacología; Caspasa 3/farmacología; Caspasa 3/uso terapéutico; Línea Celular Tumoral; Niño; Doxorrubicina/farmacología; Doxorrubicina/uso terapéutico; Humanos; Metadona/farmacología; Especies Reactivas de Oxígeno; Rabdomiosarcoma/terapia; Rabdomiosarcoma Embrionario/tratamiento farmacológico; Vincristina/farmacología

Palabras clave

Chemotherapy; Cytotoxicity; Methadone; Pediatric; Rhabdomyosarcoma

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Rabdomiosarcoma / Rabdomiosarcoma Embrionario / Antineoplásicos Tipo de estudio: Guideline Límite: Child / Humans Idioma: En Revista: J Cancer Res Clin Oncol Año: 2022 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania

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