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Pulmonary vein aneurysm in a New Zealand White rabbit: a case report.
Kim, Jong-Min; Woo, Chang Gok; Kim, Sa Hun; Jeong, Eui-Suk; Kim, Kil-Soo; Kang, Byeong-Cheol.
Afiliación
  • Kim JM; Department of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, 110-799, Korea.
  • Woo CG; Department of Pathology, Chungbuk National University College of Medicine, Cheongju, 361-763, Korea.
  • Kim SH; Department of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, 110-799, Korea.
  • Jeong ES; Laboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Republic of Korea.
  • Kim KS; Laboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Republic of Korea.
  • Kang BC; Department of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, 110-799, Korea. bckang@snu.ac.kr.
Lab Anim Res ; 38(1): 4, 2022 Feb 16.
Article en En | MEDLINE | ID: mdl-35172899
BACKGROUND: Pulmonary venous aneurysm (PVA) is a rare condition characterized by aneurysmal dilatation of the pulmonary vein in humans. The diagnosis is incidental usually as there are no clinical symptoms. This case report describes a histological diagnosis of PVA in a New Zealand White rabbit. CASE PRESENTATION: A 1.5-kg male New Zealand White rabbit was acclimatized in an animal room for 5 weeks until the experiment began. However, the rabbit was found dead, with signs of nasal hemorrhage. Necropsy revealed tracheal and pulmonary hemorrhage, and the epistaxis had a pulmonary origin. PCR and ELISA to detect antigens and antibodies pertaining to the rabbit hemorrhagic disease virus showed negative results. Multiple ballooning lesions (50-200 µm size) in the pulmonary veins were observed on histological examination, and PVA was diagnosed. Death was attributed to a spontaneous rupture of the PVA and massive hemorrhage into the lung parenchyma that extended into the trachea and nasal passages. CONCLUSIONS: To the author's best knowledge, this is the first report of a PVA in a rabbit.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Lab Anim Res Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Lab Anim Res Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido