Benzyl Isothiocyanate Attenuates Inflammasome Activation in <i>Pseudomonas aeruginosa</i> LPS-Stimulated THP-1 Cells and Exerts Regulation through the MAPKs/NF-&#954;B Pathway.

Park, Won Sun; Lee, Jeonghan; Na, Giyoun; Park, SaeGwang; Seo, Su-Kil; Choi, Jung Sik; Jung, Won-Kyo; Choi, Il-Whan

Benzyl Isothiocyanate Attenuates Inflammasome Activation in Pseudomonas aeruginosa LPS-Stimulated THP-1 Cells and Exerts Regulation through the MAPKs/NF-κB Pathway.

Park, Won Sun; Lee, Jeonghan; Na, Giyoun; Park, SaeGwang; Seo, Su-Kil; Choi, Jung Sik; Jung, Won-Kyo; Choi, Il-Whan.

Afiliación

Park WS; Department of Physiology, Kangwon National University School of Medicine, Chuncheon 24341, Korea.
Lee J; Department of Anesthesiology and Pain Medicine, Busan Paik Hospital, Inje University, Busan 47392, Korea.
Na G; Department of Microbiology and Immunology, College of Medicine, Inje University, Busan 47392, Korea.
Park S; Department of Microbiology and Immunology, College of Medicine, Inje University, Busan 47392, Korea.
Seo SK; Department of Microbiology and Immunology, College of Medicine, Inje University, Busan 47392, Korea.
Choi JS; Department of Internal Medicine, Busan Paik Hospital, Inje University, Busan 47392, Korea.
Jung WK; Department of Biomedical Engineering, Center for Marine-Integrated Biomedical Technology (BK21 Plus), Pukyong National University, Busan 48513, Korea.
Choi IW; Department of Microbiology and Immunology, College of Medicine, Inje University, Busan 47392, Korea.

Int J Mol Sci ; 23(3)2022 Jan 22.

Article en En | MEDLINE | ID: mdl-35163151

Asunto(s)

Regulación de la Expresión Génica/efectos de los fármacos; Inflamasomas/efectos de los fármacos; Isotiocianatos/farmacología; Lipopolisacáridos/efectos adversos; Proteínas Quinasas Activadas por Mitógenos/metabolismo; FN-kappa B/metabolismo; Pseudomonas aeruginosa/química; Humanos; Inflamasomas/inmunología; Inflamasomas/metabolismo; Interleucina-1beta/genética; Interleucina-1beta/metabolismo; Proteínas Quinasas Activadas por Mitógenos/genética; FN-kappa B/genética; Células THP-1

Palabras clave

Pseudomonas aeruginosa; THP-1 cells; benzyl isothiocyanate; inflammasomes; interleukin-1ß; nuclear factor-κB

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pseudomonas aeruginosa / Regulación de la Expresión Génica / Lipopolisacáridos / FN-kappa B / Isotiocianatos / Proteínas Quinasas Activadas por Mitógenos / Inflamasomas Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article Pais de publicación: Suiza

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