Innovative Bioprocess Strategies Combining Physiological Control and Strain Engineering of <i>Pichia pastoris</i> to Improve Recombinant Protein Production.

Gasset, Arnau; Garcia-Ortega, Xavier; Garrigós-Martínez, Javier; Valero, Francisco; Montesinos-Seguí, José Luis

Innovative Bioprocess Strategies Combining Physiological Control and Strain Engineering of Pichia pastoris to Improve Recombinant Protein Production.

Gasset, Arnau; Garcia-Ortega, Xavier; Garrigós-Martínez, Javier; Valero, Francisco; Montesinos-Seguí, José Luis.

Afiliación

Gasset A; Department of Chemical, Biological and Environmental Engineering, School of Engineering, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Garcia-Ortega X; Department of Chemical, Biological and Environmental Engineering, School of Engineering, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Garrigós-Martínez J; QuBi Lab, Department of Biosciences, Faculty of Sciences and Technology, Universitat de Vic-Universitat Central de Catalunya, Vic, Spain.
Valero F; Department of Chemical, Biological and Environmental Engineering, School of Engineering, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Montesinos-Seguí JL; Department of Chemical, Biological and Environmental Engineering, School of Engineering, Universitat Autònoma de Barcelona, Bellaterra, Spain.

Front Bioeng Biotechnol ; 10: 818434, 2022.

Article en En | MEDLINE | ID: mdl-35155391

Palabras clave

GAP promoter; Pichia pastoris (Komagataella phaffii); hypoxia; physiological control; recombinant gene dosage; respiratory quotient; transcriptional analysis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Bioeng Biotechnol Año: 2022 Tipo del documento: Article País de afiliación: España Pais de publicación: Suiza

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