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Lead optimization and biological evaluation of diazenylbenzenesulfonamides inhibitors against glyoxalase-I enzyme as potential anticancer agents.
Al-Oudat, Buthina A; Al-Shar'i, Nizar A; Al-Balas, Qosay A; Audat, Suaad A; Alqudah, Mohammad A Y; Hamzah, Ali H; Hallak, Ramez W; Bedi, Mel; Bryant-Friedrich, Amanda.
Afiliación
  • Al-Oudat BA; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan. Electronic address: baoudat@just.edu.jo.
  • Al-Shar'i NA; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan.
  • Al-Balas QA; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan.
  • Audat SA; Department of Chemistry, College of Science and Arts, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan.
  • Alqudah MAY; Department of Clinical Pharmacy, College of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan.
  • Hamzah AH; Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH 43606, USA.
  • Hallak RW; Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH 43606, USA.
  • Bedi M; Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH 43606, USA.
  • Bryant-Friedrich A; Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH 43606, USA.
Bioorg Chem ; 120: 105657, 2022 03.
Article en En | MEDLINE | ID: mdl-35152183
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lactoilglutatión Liasa / Antineoplásicos Idioma: En Revista: Bioorg Chem Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lactoilglutatión Liasa / Antineoplásicos Idioma: En Revista: Bioorg Chem Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos