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[Bacterial Endotoxin for Intrathoracic Medical Devices Requirement Revisited].
Lian, Xiaoqi; Shi, Xinli; Xing, Lina; Cheng, Maobo.
Afiliación
  • Lian X; Center for Medical Device Evaluation, NMPA, Beijing, 100081.
  • Shi X; Center for Medical Device Evaluation, NMPA, Beijing, 100081.
  • Xing L; Center for Medical Device Evaluation, NMPA, Beijing, 100081.
  • Cheng M; Center for Medical Device Evaluation, NMPA, Beijing, 100081.
Zhongguo Yi Liao Qi Xie Za Zhi ; 46(1): 96-98, 2022 Jan 30.
Article en Zh | MEDLINE | ID: mdl-35150117
Bacterial endotoxin is considered as one of the critical risk factors in medical devices, especially implanted devices that directly or indirectly contact with blood circulating system. In that case, endotoxin limits for implanted medical devices is important in determine the safety of medical devices. According to GB/T 14233.2-2005, the requirements of endotoxin index for intrathoracic medical devices is 2.15 EU per device. However, the definition of "intrathoracic medical devices" is vague. Specifically, "for cardiovascular system application" instead of "intrathoracic application" is more reasonable. With the deeper understanding of the risk of endotoxin in medical devices and considering the internationally accepted standards, the limits of endotoxin in medical devices for cardiovascular system application is acceptable at 20 EU per device.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Endotoxinas Idioma: Zh Revista: Zhongguo Yi Liao Qi Xie Za Zhi Año: 2022 Tipo del documento: Article Pais de publicación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Endotoxinas Idioma: Zh Revista: Zhongguo Yi Liao Qi Xie Za Zhi Año: 2022 Tipo del documento: Article Pais de publicación: China