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Fluid-Attenuated Inversion Recovery Vascular Hyperintensity as a Potential Predictor for the Prognosis of Acute Stroke Patients After Intravenous Thrombolysis.
Zhu, Lin; Jiang, Fuping; Wang, Meng; Zhai, Qian; Zhang, Qing; Wang, Feng; Mao, Xuqiang; Chen, Nihong; Zhou, Junshan; Xi, Guangjun; Shi, Yachen.
Afiliación
  • Zhu L; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
  • Jiang F; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
  • Wang M; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
  • Zhai Q; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
  • Zhang Q; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
  • Wang F; Department of Neurology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
  • Mao X; Department of Neurology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
  • Chen N; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
  • Zhou J; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
  • Xi G; Department of Neurology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
  • Shi Y; Department of Neurology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Front Neurosci ; 15: 808436, 2021.
Article en En | MEDLINE | ID: mdl-35145376
BACKGROUND: Fluid-attenuated inversion recovery vascular hyperintensity (FVH) can reflect the collateral status, which may be a valuable indicator to predict the functional outcome of acute stroke (AS) patients. METHODS: A total of 190 AS patients with large vessel occlusion (LVO) were retrospectively investigated. All patients completed a 6-month follow-up and their modified Rankin Scale (mRS) scores were recorded at 1, 3, and 6 months after intravenous thrombolysis (IVT). Based on their mRS at 3 months, patients were divided into two groups: poor prognosis (131 patients; 68.9% of all subjects) and favorable prognosis (59 patients; 31.1% of all subjects). The death records of 28 patients were also analyzed in the poor prognosis group. RESULTS: (1) Univariate and multivariate analyses showed that the higher National Institutes of Health Stroke Scale (NIHSS) score at admission, higher fasting blood glucose, and lower FVH score were independent risk factors to predict the poor prognosis of IVT. (2) Survival analysis indicated that FVH score was the only baseline factor to predict the 6-month survival after IVT. (3) Baseline FVH score had great prediction performance for the prognosis of IVT (area under the curve = 0.853). (4) Baseline FVH score were negatively correlated with the NIHSS score at discharge and mRS score at 1, 3, and 6 months. CONCLUSION: Among various baseline clinical factors, only the FVH score might have implications for 3-month outcome and 6-month survival of AS patients after IVT. Baseline FVH score showed great potential to predict the prognosis of the AS patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Neurosci Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Neurosci Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza