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A Lotus shaped acoustofluidic mixer: High throughput homogenisation of liquids in 2 ms using hydrodynamically coupled resonators.
Pourabed, Amir; Brenker, Jason; Younas, Tayyaba; He, Lizhong; Alan, Tuncay.
Afiliación
  • Pourabed A; Department of Mechanical and Aerospace Engineering, Monash University, Melbourne, Australia.
  • Brenker J; Department of Mechanical and Aerospace Engineering, Monash University, Melbourne, Australia.
  • Younas T; Department of Chemical Engineering, Monash University, Melbourne, Australia.
  • He L; Department of Chemical Engineering, Monash University, Melbourne, Australia.
  • Alan T; Department of Mechanical and Aerospace Engineering, Monash University, Melbourne, Australia. Electronic address: tuncay.alan@monash.edu.
Ultrason Sonochem ; 83: 105936, 2022 Feb.
Article en En | MEDLINE | ID: mdl-35144192
This paper presents an acoustically actuated microfluidic mixer that uses an array of hydrodynamically coupled resonators to rapidly homogenise liquid solutions and synthesise nanoparticles. The system relies on 8 identical oscillating cantilevers that are equally spaced on the perimeter of a circular well, through which the liquid solutions are introduced. When an oscillatory electrical signal is applied to a piezoelectric transducer attached to the device, the cantilevers start resonating. Due to the close proximity between the cantilevers, their circular arrangement and the liquid medium in which they are immersed, the vibration of each cantilever affects the response of its neighbours. The streaming fields and shearing rates resulting from the oscillating structures were characterised. It was shown that the system can be used to effectively mix fluids at flow rates up to 1400 µl.min-1 in time scales as low as 2 ms. The rapid mixing time is especially advantageous for nanoparticle synthesis, which is demonstrated by synthesising Poly lactide-co-glycolic acid (PLGA) nanoparticles with 52.2 nm size and PDI of 0.44.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microfluídica / Nanopartículas Idioma: En Revista: Ultrason Sonochem Asunto de la revista: DIAGNOSTICO POR IMAGEM Año: 2022 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Países Bajos
Texto completo
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Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microfluídica / Nanopartículas Idioma: En Revista: Ultrason Sonochem Asunto de la revista: DIAGNOSTICO POR IMAGEM Año: 2022 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Países Bajos