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Pre-hospital mild therapeutic hypothermia for patients with severe traumatic brain injury.
Qiu, Wusi; Chen, Mingmin; Wang, Xu; Qiu, Ws; Chen, Mm; Wang, X.
Afiliación
  • Qiu W; Department of Neurosurgery, Affiliated Hospital of Hangzhou Normal University, Zhejiang, People's Republic of China.
  • Chen M; Department of Neurosurgery, Affiliated Hospital of Hangzhou Normal University, Zhejiang, People's Republic of China.
  • Wang X; Department of Neurosurgery, Affiliated Hospital of Hangzhou Normal University, Zhejiang, People's Republic of China.
  • Qiu W; Department of Neurosurgery, Affiliated Hospital of Hangzhou Normal University, Zhejiang, People's Republic of China.
  • Chen M; Department of Emergency, Affiliated Hospital of Hangzhou Normal University, Zhejiang, People's Republic of China.
  • Wang X; Department of Neurosurgery, Affiliated Hospital of Hangzhou Normal University, Zhejiang, People's Republic of China.
Brain Inj ; 36(1): 72-76, 2022 01 02.
Article en En | MEDLINE | ID: mdl-35143363
BACKGROUND: We aimed to assess the effects of pre-hospital mild therapeutic hypothermia (MTH) on patients with severe traumatic brain injury (sTBI). METHODS: Eighty-six patients with sTBI were prospectively enrolled into the pre-hospital MTH group and the late MTH group (initiated in hospital). Patients in the pre-hospital MTH group were maintained at a tympanic temperature of 33°C-35°C before admission and continued to be treated with a therapeutic hypothermia device for 4 days. Patients in the late MTH group were treated with the same MTH parameters. Intracranial pressure (ICP), complications and Glasgow Outcome Scale (GOS) scores were monitored. RESULTS: ICP was significantly lower for patients in the pre-hospital MTH group 24, 48, and 72 h after treatment (17.38 ± 4.88 mmHg, 18.40 ± 4.50 mmHg, and 16.40 ± 4.13 mmHg, respectively) than that in the late MTH group (20.63 ± 3.00 mmHg, 21.80 ± 6.00 mmHg, and 18.81 ± 4.50 mmHg) (P < .05). The favorable prognosis (GOS scores 4-5) rate in the pre-hospital MTH group was higher tha n the late MTH group (65.1% vs. 37.2%, respectively; P < .05) without complications . CONCLUSION: Pre-hospital MTH for patients with STBI can reduce ICP and improve neurological outcomes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lesiones Traumáticas del Encéfalo / Hipotermia Inducida Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Brain Inj Asunto de la revista: CEREBRO Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lesiones Traumáticas del Encéfalo / Hipotermia Inducida Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Brain Inj Asunto de la revista: CEREBRO Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido