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SARS-CoV-2 E484K Mutation Narrative Review: Epidemiology, Immune Escape, Clinical Implications, and Future Considerations.
Yang, Wan-Ting; Huang, Wei-Hsuan; Liao, Tsai-Ling; Hsiao, Tzu-Hung; Chuang, Han-Ni; Liu, Po-Yu.
Afiliación
  • Yang WT; Division of Infection, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
  • Huang WH; Division of Infection, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
  • Liao TL; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
  • Hsiao TH; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
  • Chuang HN; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
  • Liu PY; Division of Infection, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Infect Drug Resist ; 15: 373-385, 2022.
Article en En | MEDLINE | ID: mdl-35140483
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread rapidly over the world and claimed million lives. The virus evolves constantly, and a swarm of mutants is a now major concern globally. Distinct variants could have independently converged on same mutation, despite being detected in different geographic regions, which suggested it could confer an evolutionary advantage. E484K has rapidly emerged and has frequently been detected in several SARS-CoV-2 variants of concern. In this study, we review the epidemiology and impact of E484K, its effects on neutralizing effect of several monoclonal antibodies, convalescent plasma, and post-vaccine sera.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Screening_studies Idioma: En Revista: Infect Drug Resist Año: 2022 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Nueva Zelanda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Screening_studies Idioma: En Revista: Infect Drug Resist Año: 2022 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Nueva Zelanda