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Incorrect Knowledge of Event-Driven PrEP "2-1-1" Dosing Regimen Among PrEP-Experienced Gay and Bisexual Men in Australia.
Chan, Curtis; Vaccher, Stefanie; Fraser, Doug; Grulich, Andrew E; Holt, Martin; Zablotska-Manos, Iryna; Prestage, Garrett P; Bavinton, Benjamin R.
Afiliación
  • Chan C; Kirby Institute, UNSW Sydney, Sydney, Australia.
  • Vaccher S; Kirby Institute, UNSW Sydney, Sydney, Australia.
  • Fraser D; Kirby Institute, UNSW Sydney, Sydney, Australia.
  • Grulich AE; Kirby Institute, UNSW Sydney, Sydney, Australia.
  • Holt M; The Centre for Social Research in Health, UNSW Sydney, Sydney, Australia ; and.
  • Zablotska-Manos I; Sydney Medical School, Westmead and Western Sydney Sexual Health Centre, University of Sydney, Sydney, Australia .
  • Prestage GP; Kirby Institute, UNSW Sydney, Sydney, Australia.
  • Bavinton BR; Kirby Institute, UNSW Sydney, Sydney, Australia.
J Acquir Immune Defic Syndr ; 90(2): 132-139, 2022 06 01.
Article en En | MEDLINE | ID: mdl-35135976
BACKGROUND: Event-driven pre-exposure prophylaxis (ED-PrEP), when taken according to the "2-1-1" dosing method, is highly effective at preventing HIV acquisition for gay, bisexual, and other men who have sex with men (GBM). Any missed doses when using ED-PrEP drastically reduce its effectiveness, so it is vital that people using this method know how to take it correctly. This study investigated Australian GBM's awareness of ED-PrEP and their knowledge of how to take it correctly. METHOD: We conducted a survey of 1471 PrEP-experienced GBM in Australia, between October 2019 and March 2020. The survey assessed awareness and knowledge of the 3 components of the "2-1-1" ED-PrEP dosing regimen (number of pills for loading dose, timing of loading dose, and number of days after sex to take PrEP pills) among GBM. Characteristics associated with ED-PrEP awareness and correct knowledge of how to take ED-PrEP were assessed with multivariate logistic regression. RESULTS: Two-thirds (n = 1004, 68.4%) had heard of ED-PrEP, of whom only one-eighth (n = 125, 12.5%) knew the correct details of the "2-1-1" ED-PrEP method; one-third (n = 339, 33.8%) did not know any of the 3 key components. Awareness of ED-PrEP and correct knowledge was associated with greater belief in PrEP efficacy, university education, and intention to take a nondaily PrEP regimen in the next 6 months. CONCLUSIONS: Although ED-PrEP awareness was considerable, most participants did not know how to use ED-PrEP correctly. Further work is needed to increase awareness and knowledge of ED-PrEP among GBM.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Profilaxis Pre-Exposición / Minorías Sexuales y de Género Límite: Humans / Male País/Región como asunto: Oceania Idioma: En Revista: J Acquir Immune Defic Syndr Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Año: 2022 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Profilaxis Pre-Exposición / Minorías Sexuales y de Género Límite: Humans / Male País/Región como asunto: Oceania Idioma: En Revista: J Acquir Immune Defic Syndr Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Año: 2022 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Estados Unidos