Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology.

Liu, Sen; Fan, Min; Xu, Jing-Xian; Yang, Long-Jun; Qi, Cong-Cong; Xia, Qing-Rong; Ge, Jin-Fang

Liu, Sen; Fan, Min; Xu, Jing-Xian; Yang, Long-Jun; Qi, Cong-Cong; Xia, Qing-Rong; Ge, Jin-Fang.

Afiliación

Liu S; School of Pharmacy, Anhui Medical University, 81 Meishan Road, Anhui, 230032, Hefei, People's Republic of China.
Fan M; The Key Laboratory of Anti-Inflammatory and Immune Medicine, Ministry of Education, Anhui Medical University, Hefei, China.
Xu JX; Anhui Provincial Laboratory of Inflammatory and Immunity Disease, Anhui Institute of Innovative Drugs, Hefei, China.
Yang LJ; School of Pharmacy, Anhui Medical University, 81 Meishan Road, Anhui, 230032, Hefei, People's Republic of China.
Qi CC; The Key Laboratory of Anti-Inflammatory and Immune Medicine, Ministry of Education, Anhui Medical University, Hefei, China.
Xia QR; Anhui Provincial Laboratory of Inflammatory and Immunity Disease, Anhui Institute of Innovative Drugs, Hefei, China.
Ge JF; School of Pharmacy, Anhui Medical University, 81 Meishan Road, Anhui, 230032, Hefei, People's Republic of China.

J Neuroinflammation ; 19(1): 35, 2022 Feb 07.

Article en En | MEDLINE | ID: mdl-35130907

Asunto(s)

Enfermedad de Alzheimer; Factor Neurotrófico Derivado del Encéfalo/metabolismo; Disfunción Cognitiva; Exosomas; Células Madre Mesenquimatosas; Enfermedades Neurodegenerativas; Enfermedad de Alzheimer/metabolismo; Enfermedad de Alzheimer/terapia; Animales; Médula Ósea; Disfunción Cognitiva/metabolismo; Disfunción Cognitiva/terapia; Exosomas/metabolismo; Células Madre Mesenquimatosas/metabolismo; Ratones; Ratones Endogámicos C57BL; Enfermedades Neurodegenerativas/metabolismo

Palabras clave

Alzheimer's disease; Bone-marrow stem cell; Exosome; Neuroinflammation; Synaptic plasticity

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor Neurotrófico Derivado del Encéfalo / Enfermedades Neurodegenerativas / Exosomas / Células Madre Mesenquimatosas / Enfermedad de Alzheimer / Disfunción Cognitiva Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Neuroinflammation Asunto de la revista: NEUROLOGIA Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido

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