Cardiac Gene Therapy With Relaxin Receptor 1 Overexpression Protects Against Acute Myocardial Infarction.

Devarakonda, Teja; Mauro, Adolfo G; Cain, Chad; Das, Anindita; Salloum, Fadi N

Cardiac Gene Therapy With Relaxin Receptor 1 Overexpression Protects Against Acute Myocardial Infarction.

Devarakonda, Teja; Mauro, Adolfo G; Cain, Chad; Das, Anindita; Salloum, Fadi N.

Afiliación

Devarakonda T; Pauley Heart Center, Division of Cardiology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Mauro AG; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, USA.
Cain C; Pauley Heart Center, Division of Cardiology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Das A; Pauley Heart Center, Division of Cardiology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Salloum FN; Pauley Heart Center, Division of Cardiology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.

JACC Basic Transl Sci ; 7(1): 53-63, 2022 Jan.

Article en En | MEDLINE | ID: mdl-35128209

Palabras clave

AAV, adeno-associated virus; CMV, cytomegalovirus; GLS, global longitudinal strain; IR, ischemia-reperfusion; LV function; LV, left ventricular; MAPK, mitogen-activated protein kinase; MI, myocardial infarction; PV, pressure-volume; RXFP1; RXFP1, relaxin family peptide receptor 1; SIRO, simulated ischemia and reoxygenation; VEC, empty vector; eNOS, endothelial nitric oxide synthase; gene therapy; ischemia-reperfusion injury; mRNA, messenger ribonucleic acid; relaxin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: JACC Basic Transl Sci Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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