Limited astrocyte-to-neuron conversion in the mouse brain using NeuroD1 overexpression.

Leib, David; Chen, Yong Hong; Monteys, Alex Mas; Davidson, Beverly L

Leib, David; Chen, Yong Hong; Monteys, Alex Mas; Davidson, Beverly L.

Afiliación

Leib D; Raymond G. Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Chen YH; Raymond G. Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Monteys AM; Raymond G. Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Davidson BL; Raymond G. Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. Electronic address: davidsonbl@c

Mol Ther ; 30(3): 982-986, 2022 03 02.

Article en En | MEDLINE | ID: mdl-35123657

Asunto(s)

Astrocitos; Neuronas; Animales; Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico/genética; Encéfalo; Ratones

Palabras clave

adeno-associated virus; astrocytes; conversion; gene therapy; neurodegeneration; neurons; transdifferentiation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Astrocitos / Neuronas Límite: Animals Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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