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Optical coherence tomography angiography in healthy children: normative data and age-related changes in microvascular structure of the optic disk and macula.
Kurumoglu Incekalan, Tugba; Naz Simdivar, Göksu Hande; Çelik, Ümit; Alyamaç Sukgen, Emine; Özdemir, Ulas.
Afiliación
  • Kurumoglu Incekalan T; Department of Opthalmology, University of Health Sciences Adana City Training and Research Hospital, Adana, Turkey. tugbakurumoglu@hotmail.com.
  • Naz Simdivar GH; Department of Opthalmology, University of Health Sciences Adana City Training and Research Hospital, Adana, Turkey.
  • Çelik Ü; Pediatric Infectious Diseases, University of Health Sciences Adana City Training and Research Hospital, Adana, Turkey.
  • Alyamaç Sukgen E; Department of Opthalmology, University of Health Sciences Adana City Training and Research Hospital, Adana, Turkey.
  • Özdemir U; Department of Pediatrics, University of Health Sciences Adana City Training and Research Hospital, Adana, Turkey.
Int Ophthalmol ; 42(8): 2373-2383, 2022 Aug.
Article en En | MEDLINE | ID: mdl-35122180
PURPOSE: To determine normative data and reference ranges according to age groups by measuring the foveal avascular zone (FAZ), superficial capillary plexus vascular density (SCP-VD), deep capillary plexus vascular density (DVP-VD), radial peripapillary capillary plexus vessel density (RPC-VD), and peripapillary retinal nerve fiber layer (ppRNFL) in healthy children and to determine the age and sex-related changes of these values. METHODS: This prospective study included data from 370 eyes of 370 healthy children (202 girls, 168 boys) aged 7-18 years. Participants were divided into four groups according to their age. Optical coherence tomography angiography (OCTA) measurements were taken using AngioVue (Avanti; Optivue). RESULTS: No statistically significant difference was observed in terms of FAZ, SCP-VD, DCP-VD, RPC-VD, and ppRNFL thickness values according to the age groups (except the RPC-VD superior) (p > 0.05 for all). VDs in all deep parafoveal regions in groups 1 and 2 were higher in girls. While FAZ values were higher in girls in all age groups (statistically significant in groups 1, 3, and 4), ad SPD and DPD values were higher in boys in all age groups (statistically significant in group 1 and 2 for SPD, and group 1 and 3 for DPD). CONCLUSIONS: We report normal reference ranges for macula and disk vessel density and ppRNFL parameters in healthy children aged 7-18 years using OCTA. These normative values could be useful in diagnosing retina and optic disk disease early in childhood.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Disco Óptico Tipo de estudio: Observational_studies Límite: Child / Female / Humans / Male Idioma: En Revista: Int Ophthalmol Año: 2022 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Disco Óptico Tipo de estudio: Observational_studies Límite: Child / Female / Humans / Male Idioma: En Revista: Int Ophthalmol Año: 2022 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Países Bajos