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Vasomotor symptoms in early breast cancer-a "real world" exploration of the patient experience.
Cole, Katherine Marie; Clemons, Mark; Alzahrani, Mashari; Liu, Michelle; Larocque, Gail; MacDonald, Fiona; Hutton, Brian; Piper, Ardelle; Fernandes, Ricardo; Pond, Gregory R; Vandermeer, Lisa; Emam, Khaled El; McGee, Sharon F.
Afiliación
  • Cole KM; Division of Medical Oncology, Department of Medicine, The Ottawa Hospital, The University of Ottawa, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.
  • Clemons M; Division of Medical Oncology, Department of Medicine, The Ottawa Hospital, The University of Ottawa, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.
  • Alzahrani M; Cancer Therapeutics Program, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • Liu M; Division of Medical Oncology, Department of Medicine, The Ottawa Hospital, The University of Ottawa, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.
  • Larocque G; Cancer Therapeutics Program, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • MacDonald F; The Ottawa Hospital Cancer Centre, Ottawa, ON, Canada.
  • Hutton B; The Ottawa Hospital Cancer Centre, Ottawa, ON, Canada.
  • Piper A; Clinical Epidemiology Program, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • Fernandes R; University of Ottawa Health Services, Ottawa, ON, Canada.
  • Pond GR; Division of Medical Oncology, Department of Oncology, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
  • Vandermeer L; Department of Oncology, McMaster University, Hamilton, ON, Canada.
  • Emam KE; Cancer Therapeutics Program, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • McGee SF; CHEO Research Institute and the School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.
Support Care Cancer ; 30(5): 4437-4446, 2022 May.
Article en En | MEDLINE | ID: mdl-35112212
BACKGROUND: Despite the frequency of vasomotor symptoms (VMS) in patients with early breast cancer (EBC), their optimal management remains unknown. A patient survey was performed to determine perspectives on this important clinical challenge. METHODS: Patients with EBC experiencing VMS participated in an anonymous survey. Patients reported on the frequency and severity of VMS using the validated Hot Flush Rating Scale (HFRS) and ranked their most bothersome symptoms. Respondents were also asked to determine endpoints that defined effective treatment of VMS and report on the effectiveness of previously tried interventions. RESULTS: Responses were received from 373 patients, median age 56 years (range 23-83), who experienced an average of 5.0 hot flashes per day (SD 6.57). Patients reported the most bothersome symptoms to be feeling hot/sweating (155/316, 49%) and sleeping difficulties (86/316, 27%). Fifty-five percent (201/365) of patients would consider a treatment to be effective if it reduced night-time awakenings. While 68% of respondents were interested in trying interventions from their healthcare team to manage VMS, only 18% actually did so. Of the 137 patients who had tried an intervention for VMS, pharmacological treatments, exercise, and relaxation strategies were more likely to be effective, while therapies such as melatonin and black cohosh were deemed less effective. CONCLUSION: VMS are a common and bothersome problem for EBC patients, with a minority receiving interventions to manage these symptoms. Further research is needed to identify patient-centered strategies for managing these distressing symptoms.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama Tipo de estudio: Diagnostic_studies / Etiology_studies Límite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Revista: Support Care Cancer Asunto de la revista: NEOPLASIAS / SERVICOS DE SAUDE Año: 2022 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama Tipo de estudio: Diagnostic_studies / Etiology_studies Límite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Revista: Support Care Cancer Asunto de la revista: NEOPLASIAS / SERVICOS DE SAUDE Año: 2022 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Alemania