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A Pilot Study on The Effect of a Novel Feed Additive Containing Exogenous Enzymes, Acidifiers, Sodium Butyrate and Silicon Dioxide Nanoparticles on Selected Cellular Immune Indices and Body Weight Gains of Calves.
Szacawa, Ewelina; Dudek, Katarzyna; Bednarek, Dariusz; Pieszka, Marek; Bederska-Lojewska, Dorota.
Afiliación
  • Szacawa E; Department of Cattle and Sheep Diseases, National Veterinary Research Institute, Pulawy, Poland.
  • Dudek K; Department of Cattle and Sheep Diseases, National Veterinary Research Institute, Pulawy, Poland.
  • Bednarek D; Department of Cattle and Sheep Diseases, National Veterinary Research Institute, Pulawy, Poland.
  • Pieszka M; Department of Animal Nutrition and Feed Science, National Research Institute of Animal Production, Balice, Poland.
  • Bederska-Lojewska D; Department of Animal Nutrition and Feed Science, National Research Institute of Animal Production, Balice, Poland.
J Vet Res ; 65(4): 497-504, 2021 Dec.
Article en En | MEDLINE | ID: mdl-35112005
INTRODUCTION: The rearing of calves is a difficult period for farmers due to health problems to which the animals are prone this time. Since the use of antibiotics as growth promoters has been forbidden, various innovative feed additives have been tested in many countries around the world. MATERIAL AND METHODS: In this study, experimental (E) calves were supplemented with a novel feed additive consisting of the pancreatic-like enzymes protease and lipase, a fat-coated mixture of organic fumaric, malic, citric and sorbic acids, sodium butyrate and silicon dioxide nanoparticles. Control (C) calves received feed without additive. During the supplementation, white blood cell (WBC) counts with leukocyte differentiation, percentages of B lymphocytes and T lymphocytes and their subpopulations, phagocytic activity and oxidative burst of circulating monocytes and granulocytes were examined. Body weight (b.w.) gains of the calves were also monitored. RESULTS: The WBC counts in the E and C calves were within the reference ranges throughout the study. In the analysis of the percentages of the lymphocyte subpopulations, phagocytic activity and oxidative burst, no statistically significant differences were reported between the E and C groups. However, higher average daily body weight gains were obtained for the E calves. CONCLUSION: The study revealed that the examined feed additive did not modulate the immune response of the calves significantly. The tendency to higher daily average b.w. gains in the E calves than in the C calves suggests a beneficial effect of this feed additive.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: J Vet Res Año: 2021 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Polonia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: J Vet Res Año: 2021 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Polonia