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Loss of TET reprograms Wnt signaling through impaired demethylation to promote lung cancer development.
Xu, Qin; Wang, Chao; Zhou, Jia-Xin; Xu, Zhi-Mei; Gao, Juan; Sui, Pengfei; Walsh, Colum P; Ji, Hongbin; Xu, Guo-Liang.
Afiliación
  • Xu Q; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
  • Wang C; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
  • Zhou JX; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
  • Xu ZM; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
  • Gao J; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
  • Sui P; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
  • Walsh CP; Genomic Medicine Research Group, Biomedical Sciences, Ulster University, Coleraine BT52 1SA, United Kingdom.
  • Ji H; Centre for Research & Development, Region Gävleborg/Uppsala University, Gävle 801 88, Sweden.
  • Xu GL; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China; hbji@sibcb.ac.cn glxu@sibcb.ac.cn.
Proc Natl Acad Sci U S A ; 119(6)2022 02 08.
Article en En | MEDLINE | ID: mdl-35110400
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN de Neoplasias / Proteínas Proto-Oncogénicas / Metilación de ADN / Vía de Señalización Wnt / Adenocarcinoma del Pulmón / Neoplasias Pulmonares / Neoplasias Experimentales Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN de Neoplasias / Proteínas Proto-Oncogénicas / Metilación de ADN / Vía de Señalización Wnt / Adenocarcinoma del Pulmón / Neoplasias Pulmonares / Neoplasias Experimentales Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos