Enhancement of l-Pipecolic Acid Production by Dynamic Control of Substrates and Multiple Copies of the <i>pipA</i> Gene in the <i>Escherichia coli</i> Genome.

Xu, Xin; Rao, Zhi-Ming; Xu, Jian-Zhong; Zhang, Wei-Guo

Enhancement of l-Pipecolic Acid Production by Dynamic Control of Substrates and Multiple Copies of the pipA Gene in the Escherichia coli Genome.

Xu, Xin; Rao, Zhi-Ming; Xu, Jian-Zhong; Zhang, Wei-Guo.

Afiliación

Xu X; The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800# Lihu Road, Wuxi 214122, People's Republic of China.
Rao ZM; The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800# Lihu Road, Wuxi 214122, People's Republic of China.
Xu JZ; National Engineering Laboratory for Cereal Fermentation Technology (NELCF), Jiangnan University, 1800# Lihu Road, Wuxi 214122, People's Republic of China.
Zhang WG; The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800# Lihu Road, Wuxi 214122, People's Republic of China.

ACS Synth Biol ; 11(2): 760-769, 2022 02 18.

Article en En | MEDLINE | ID: mdl-35073050

Asunto(s)

Escherichia coli; Ingeniería Metabólica; Escherichia coli/genética; Escherichia coli/metabolismo; Fermentación; Ingeniería Metabólica/métodos; Ácidos Pipecólicos/química; Ácidos Pipecólicos/metabolismo

Palabras clave

Tn5 transposon; fed-batch cultivation; l-lysine cyclodeaminase; l-lysine riboswitch; l-pipecolic acid; tetA dual genetic selection

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Escherichia coli / Ingeniería Metabólica Idioma: En Revista: ACS Synth Biol Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos

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