Exploring Dendrimer Nanoparticles for Chronic Wound Healing.

Tetteh-Quarshie, Samuel; Blough, Eric R; Jones, Cynthia B

Tetteh-Quarshie, Samuel; Blough, Eric R; Jones, Cynthia B.

Afiliación

Tetteh-Quarshie S; Department of Pharmaceutical Science and Research, School of Pharmacy, Marshall University, Huntington, WV, United States.
Blough ER; Department of Pharmaceutical Science and Research, School of Pharmacy, Marshall University, Huntington, WV, United States.
Jones CB; Department of Pharmacology, Physiology, and Toxicology, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV, United States.

Front Med Technol ; 3: 661421, 2021.

Article en En | MEDLINE | ID: mdl-35047918

RESUMEN

The United States spends billions of dollars to treat chronic wounds each year. Wound healing is complex in nature which involves several intricate multiphase processes that can be delayed for a number of reasons leading to the development of chronic wounds. Wound healing therapies range from topical preparations to surgical repair with treatment options that vary based on other underlying factors like co-infection, age, or co-morbidities such as diabetes. Historically, micelles and liposomes are some of the nanoparticle drug delivery systems explored to treat chronic wounds; however, recent data suggests that dendrimers have shown potential to rival these systems in treating chronic wounds as well as other diseases. This mini review examines advances in dendrimer nanoparticle drug delivery systems to treat chronic wounds.

Palabras clave

chronic wounds; dendrimers; nanoparticles; silver nanocomposite-dendrimer; wound healing

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Med Technol Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

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