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Crystal structure of the α1B-adrenergic receptor reveals molecular determinants of selective ligand recognition.
Deluigi, Mattia; Morstein, Lena; Schuster, Matthias; Klenk, Christoph; Merklinger, Lisa; Cridge, Riley R; de Zhang, Lazarus A; Klipp, Alexander; Vacca, Santiago; Vaid, Tasneem M; Mittl, Peer R E; Egloff, Pascal; Eberle, Stefanie A; Zerbe, Oliver; Chalmers, David K; Scott, Daniel J; Plückthun, Andreas.
Afiliación
  • Deluigi M; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.
  • Morstein L; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.
  • Schuster M; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.
  • Klenk C; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.
  • Merklinger L; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.
  • Cridge RR; Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, 2800 Kgs, Lyngby, Denmark.
  • de Zhang LA; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, 30 Royal Parade, Parkville, VIC, 3052, Australia.
  • Klipp A; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, 30 Royal Parade, Parkville, VIC, 3052, Australia.
  • Vacca S; Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, VIC, 3010, Australia.
  • Vaid TM; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.
  • Mittl PRE; Department of Chemistry and Applied Biosciences, ETH Zurich, Vladimir-Prelog-Weg 1-5/10, CH-8093, Zurich, Switzerland.
  • Egloff P; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.
  • Eberle SA; Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL, USA.
  • Zerbe O; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.
  • Chalmers DK; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.
  • Scott DJ; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.
  • Plückthun A; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
Nat Commun ; 13(1): 382, 2022 01 19.
Article en En | MEDLINE | ID: mdl-35046410
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Adrenérgicos alfa 1 / Cristalografía por Rayos X Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Adrenérgicos alfa 1 / Cristalografía por Rayos X Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido