Your browser doesn't support javascript.
loading
New Synthetic Method and Insecticidal Activities of Novel Imidazopyridine Mesoionic Derivatives Containing an Ester Group.
Liu, Zhengjun; Song, Runjiang; Zhang, Desheng; Wu, Rong; Liu, Ting; Wu, Zhengxue; Song, Baoan.
Afiliación
  • Liu Z; State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
  • Song R; College of Chemistry and Chemical Engineering, Anshun University, Anshun, Guizhou 561000, China.
  • Zhang D; State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
  • Wu R; State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
  • Liu T; State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
  • Wu Z; State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
  • Song B; State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
J Agric Food Chem ; 70(4): 1019-1028, 2022 Feb 02.
Article en En | MEDLINE | ID: mdl-35041404
To develop novel insecticides with high efficiency, a new mode of action, and safety to nontarget organisms and the environment, a series of imidazopyridine mesoionic compounds containing an ester group have been designed and synthesized via a new synthetic method discovered by our group. The bioactivity results showed that most of the target compounds exhibited significant insecticidal activities against Aphis craccivora, and some of them showed moderate insecticidal activities against Sogatella furcifera. Among them, compounds C2, C4-C11, and D3 showed excellent insecticidal activities against A. craccivora (LC50 values were lower than 4.5 µg/mL), which were superior to those of pymetrozine (LC50 = 6.19 µg/mL) and triflumezopyrim (LC50 = 4.68 µg/mL). Remarkably, the insecticidal activity of compound C9 was 5.9-fold greater than that of triflumezopyrim with an LC50 value of 0.8 µg/mL. Proteomics and molecular docking results indicated that compound C9 may affect the nervous system of A. craccivora and act on nicotinic acetylcholine receptors like triflumezopyrim.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Áfidos / Insecticidas Límite: Animals Idioma: En Revista: J Agric Food Chem Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Áfidos / Insecticidas Límite: Animals Idioma: En Revista: J Agric Food Chem Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos