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Modeling uniquely human gene regulatory function via targeted humanization of the mouse genome.
Dutrow, Emily V; Emera, Deena; Yim, Kristina; Uebbing, Severin; Kocher, Acadia A; Krenzer, Martina; Nottoli, Timothy; Burkhardt, Daniel B; Krishnaswamy, Smita; Louvi, Angeliki; Noonan, James P.
Afiliación
  • Dutrow EV; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.
  • Emera D; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Yim K; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.
  • Uebbing S; Center for Reproductive Longevity and Equality, Buck Institute for Research on Aging, Novato, CA, 94945, USA.
  • Kocher AA; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.
  • Krenzer M; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.
  • Nottoli T; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.
  • Burkhardt DB; Department of Genetics, Yale School of Medicine, New Haven, CT, 06510, USA.
  • Krishnaswamy S; Neuroscience Research Training Program, Department of Psychiatry, Yale School of Medicine, New Haven, CT, 06510, USA.
  • Louvi A; Department of Comparative Medicine, Yale School of Medicine, New Haven, CT, 06510, USA.
  • Noonan JP; Yale Genome Editing Center, Yale School of Medicine, New Haven, CT, 06510, USA.
Nat Commun ; 13(1): 304, 2022 01 13.
Article en En | MEDLINE | ID: mdl-35027568

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regulación de la Expresión Génica / Genoma / Modelos Genéticos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regulación de la Expresión Génica / Genoma / Modelos Genéticos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido