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Profile of Neurological Manifestations in Children Presenting with Rickettsial Disease.
Chiranth, S B; Ashwini, K R; Gowda, Vykuntraju K; Sanjay, K S; Ahmed, Maaz; Basavaraja, G V.
Afiliación
  • Chiranth SB; Department of Pediatric Medicine, Indira Gandhi Institute of Child Health, Bangalore, Karnataka.
  • Ashwini KR; Department of Pediatric Medicine, Indira Gandhi Institute of Child Health, Bangalore, Karnataka.
  • Gowda VK; Department of Pediatric Neurology, Indira Gandhi Institute of Child Health, Bangalore, Karnataka.
  • Sanjay KS; Department of Pediatric Medicine, Indira Gandhi Institute of Child Health, Bangalore, Karnataka.
  • Ahmed M; Department of Pediatric Medicine, Indira Gandhi Institute of Child Health, Bangalore, Karnataka.
  • Basavaraja GV; Department of Pediatric Medicine, Indira Gandhi Institute of Child Health, Bangalore, Karnataka. Correspondence to: Prof GV Basavaraja, Pediatric Medicine, Indira Gandhi Institute of Child Health, Bangalore, Karnataka. basavgv@gmail.com.
Indian Pediatr ; 59(3): 222-225, 2022 03 15.
Article en En | MEDLINE | ID: mdl-35014614
OBJECTIVE: To study the profile of neurological manifestation of rickettsial disease in children. METHODS: Review of hospital records was done in a tertiary care hospital for the period from January to December, 2020. Data of all the children fulfilling the inclusion criteria i.e., clinical criteria and serology were retrieved from the hospital records. RESULTS: Of the total 7974 children admitted over this period, 178 were diagnosed with rickettsial disease wherein 54 (33.3%) had neurological involvement. Convulsions (59%), altered sensorium (56%), headache (44%), meningeal signs (37%), ataxia, (11%), lateral rectus palsy (7.5%) and stroke (7.5%) were the major neurological manifestations. Cerebrospinal fluid (CSF) analysis done in 30 (55%) children showed pleocytosis [median (IQR) cells 15 (3.75, 50)] with lymphocyte predominance [median (IQR) lymphocytes 11.5 (3, 38.75)] and elevated proteins [median IQR 41.5 (29.75,61)]. Neuroimaging abnormalities noticed were cerebral edema (n=7), cerebellar hyperintensities (n=5), basal ganglia infarcts (n=2) and hippocampal hyperintensities (n=1). CONCLUSION: Early recognition of rickettsial infection as a cause of neurological manifestation would facilitate early specific management.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Rickettsia / Neuroimagen Tipo de estudio: Diagnostic_studies Límite: Child / Humans Idioma: En Revista: Indian Pediatr Año: 2022 Tipo del documento: Article Pais de publicación: India
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Rickettsia / Neuroimagen Tipo de estudio: Diagnostic_studies Límite: Child / Humans Idioma: En Revista: Indian Pediatr Año: 2022 Tipo del documento: Article Pais de publicación: India